Thymoma history and symptoms: Difference between revisions

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*[[Chest pain]] (due to local compression of the mass itself)
*[[Chest pain]] (due to local compression of the mass itself)
===Sympotms related to associated autoimmune diseases===
===Sympotms related to associated autoimmune diseases===
30% of patients have their tumors discovered because they have an associated autoimmune disorder, these symptoms may inculde:
30% of patients have their tumors discovered because they have an associated autoimmune disorder, these symptoms may include:
*Muscle weakness (associated with [[myasthenia gravis]] and [[polymyositis]])
*Muscle weakness (associated with [[myasthenia gravis]] and [[polymyositis]])
*Anemia (associated with [[pure red cell aplasia]])
*Anemia (associated with [[pure red cell aplasia]])
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33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified on a [[chest X-ray]] performed for an unrelated problem.<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified on a [[chest X-ray]] performed for an unrelated problem.<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>


{| {{table}}
|+ List of autoimmune diseases associated<ref>{{Cite web  | last =  | first =  | title = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/BB10.pdf | url = http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb10/BB10.pdf | publisher =  | date =  | accessdate = }}</ref>
| style="width: 25%;"| '''Type'''
| style="width: 75%;"| '''Diseases'''
|-
| Neuromuscular Diseases ||[[Myasthenia gravis]], [[neuromyotonia]], rippling muscle disease, [[polymyositis]]/[[dermatomyositis]], [[encephalitis]] (limbic, cortical and brain stem), [[intestinal pseudoobstruction]].
|-
| Haematologic Autoimmune Diseases ||[[Anemia]]: [[pure red cell aplasia]], [[pernicious anemia]], [[hemolytic anemia]] and [[aplastic anemia]]. Other isolated cytopenis: [[esinophils]], [[basophils]] and [[neutrophils]]. Immunodeficiencies: [[hypogammaglobulinaemia]] +/- T-cell deficiencies ([[Good syndrome]]).
|-
| Dermatologic Diseases ||[[Pemphigus]] (foliaceus or paraneoplastic), [[lichen planus]], [[alopecia areata]].
|-
| Endocrine Disorders ||[[Addison disease]], [[graves disease]] and [[Cushing disease]].
|-
| Renal and Hepatic Diseases ||[[Glomerulonephritis]] and [[autoimmune hepatitis]].
|-
| Systemic Autoimmune Diseases ||[[SLE]], [[Sjögren syndrome]], [[systemic sclerosis]] and [[graft-versus-host-disease]].
|}


==References==
==References==

Revision as of 16:55, 22 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2]

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Symptoms related to compression

30% of patients with a thymoma have symptoms caused by compression of the surrounding organs, these symptoms may include:[1]

Sympotms related to associated autoimmune diseases

30% of patients have their tumors discovered because they have an associated autoimmune disorder, these symptoms may include:

Lack of symptoms

33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified on a chest X-ray performed for an unrelated problem.[1]


References

  1. 1.0 1.1 Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter |month= ignored (help)


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