Angiomyolipoma medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
There is no treatment for [[angiomyolipoma]]; the mainstay of therapy is embolisation or resection. | There is no treatment for [[angiomyolipoma]]; the mainstay of therapy is [[embolisation]] or resection. | ||
==Treatment== | ==Treatment== | ||
Angiomyolipomas found incidentally usually require no therapy | There is no treatment for [[angiomyolipoma]]; the mainstay of therapy is [[embolisation]] or resection. Angiomyolipomas found incidentally usually require no therapy | ||
Patients with kidney loss should be monitored for: | |||
*Hypertension | |||
*Nephrotoxic drugs such as: | |||
**Certain pain relievers | |||
**IV contrast agents | |||
===[[Rapamycin]]=== | |||
[[Rapamycin]] and related drugs have been studied for their effect on angiomyolipomas due to their action on the pathways that are disrupted when TSC1 and TSC2 genes are broken | [[Rapamycin]] and related drugs have been studied for their effect on angiomyolipomas due to their action on the pathways that are disrupted when ''TSC1'' and ''TSC2'' genes are broken.<ref name=Bissler2010>Bissler JJ, Henske EP. Renal Manifestations of Tuberous Sclerosis Complex. In: Kwiatkowski DJ, Wiittlemore DJ, Thiele EA, editors. Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics. Wiley-VCH Verlag GmbH; 2010. p. 321–325. ISBN 3-527-32201-9.</ref> | ||
==References== | ==References== | ||
Revision as of 19:22, 22 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
There is no treatment for angiomyolipoma; the mainstay of therapy is embolisation or resection.
Treatment
There is no treatment for angiomyolipoma; the mainstay of therapy is embolisation or resection. Angiomyolipomas found incidentally usually require no therapy Patients with kidney loss should be monitored for:
- Hypertension
- Nephrotoxic drugs such as:
- Certain pain relievers
- IV contrast agents
Rapamycin
Rapamycin and related drugs have been studied for their effect on angiomyolipomas due to their action on the pathways that are disrupted when TSC1 and TSC2 genes are broken.[1]
References
- ↑ Bissler JJ, Henske EP. Renal Manifestations of Tuberous Sclerosis Complex. In: Kwiatkowski DJ, Wiittlemore DJ, Thiele EA, editors. Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics. Wiley-VCH Verlag GmbH; 2010. p. 321–325. ISBN 3-527-32201-9.