Acoustic neuroma classification: Difference between revisions
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==Classification== | ==Classification== | ||
Based on the [[MRI scan]], acoustic neuromas can be classified into three subtypes: | Based on the [[MRI scan]], acoustic neuromas can be classified into three subtypes: | ||
*Entirely intracanalicular: The entire tumor is completely within the bony canal | *Entirely intracanalicular: The entire tumor is completely within the bony canal | ||
*Intracranial extension without [[brain stem]] distortion | *Intracranial extension without [[brain stem]] distortion | ||
*Intracranial extension with brain stem distortion | *Intracranial extension with brain stem distortion | ||
Based on microscopic [[histopathology]], acoustic neuroma can be classified into four subtypes:<ref name="pmid12792904">{{cite journal| author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM| title=The pathobiologic spectrum of Schwannomas. | journal=Histol Histopathol | year= 2003 | volume= 18 | issue= 3 | pages= 925-34 | pmid=12792904 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12792904 }} </ref> | Based on microscopic [[histopathology]], acoustic neuroma can be classified into four subtypes:<ref name="pmid12792904">{{cite journal| author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM| title=The pathobiologic spectrum of Schwannomas. | journal=Histol Histopathol | year= 2003 | volume= 18 | issue= 3 | pages= 925-34 | pmid=12792904 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12792904 }} </ref> | ||
*Conventional [[schwannoma]] | *Conventional [[schwannoma]] | ||
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*Plexiform schwannoma | *Plexiform schwannoma | ||
*Melanotic schwannoma | *Melanotic schwannoma | ||
**Conventional schwannoma: It is the most common | **Conventional schwannoma: It is the most common | ||
**Cellular schwannoma: It may mimic [[malignant]] peripheral nerve sheath tumor | **Cellular schwannoma: It may mimic [[malignant]] peripheral nerve sheath tumor | ||
**Plexiform schwannoma: It may mimic malignant peripheral nerve sheath [[tumor]] if cellular- especially in childhood | **Plexiform schwannoma: It may mimic malignant peripheral nerve sheath [[tumor]] if cellular- especially in childhood[[File:Plexiform_schwannoma_with_high_magnifaction.jpg|thumb|none|800px|Plexiform schwannoma with high magnifaction]] | ||
**Melanotic schwannoma: It may be confused with [[melanoma]]. [[File:Psammomatous_melanotic_schwannoma.jpg|thumb|none|800px|Psammomatous melanotic schwannoma]] | **Melanotic schwannoma: It may be confused with [[melanoma]]. [[File:Psammomatous_melanotic_schwannoma.jpg|thumb|none|800px|Psammomatous melanotic schwannoma]] | ||
It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). | It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). | ||
Revision as of 19:53, 23 September 2015
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Acoustic neuroma Microchapters | |
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Diagnosis | |
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Case Studies | |
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Acoustic neuroma classification On the Web | |
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American Roentgen Ray Society Images of Acoustic neuroma classification | |
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Risk calculators and risk factors for Acoustic neuroma classification | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Acoustic neuroma may be classified into three subtypes based on MRI scan, and into four subtypes based on microscopic histopathology.[1]
Classification
Based on the MRI scan, acoustic neuromas can be classified into three subtypes:
- Entirely intracanalicular: The entire tumor is completely within the bony canal
- Intracranial extension without brain stem distortion
- Intracranial extension with brain stem distortion
Based on microscopic histopathology, acoustic neuroma can be classified into four subtypes:[2]
- Conventional schwannoma
- Cellular schwannoma
- Plexiform schwannoma
- Melanotic schwannoma
- Conventional schwannoma: It is the most common
- Cellular schwannoma: It may mimic malignant peripheral nerve sheath tumor
- Plexiform schwannoma: It may mimic malignant peripheral nerve sheath tumor if cellular- especially in childhood
Plexiform schwannoma with high magnifaction - Melanotic schwannoma: It may be confused with melanoma.
Psammomatous melanotic schwannoma
It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). The Carney complex, also known as Carney syndrome, NAME syndrome and LAMB syndrome, is a bunch of things that occur together due to some genetic problem. It consists of:
- Cutaneous lentigines
- Myxomas (skin (subcutaneous), subcutanous, heart)
- Endocrine neoplasms[3]
References
- ↑ "Libre Pathology schwannoma acoustic neuroma subtypes".
- ↑ Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM (2003). "The pathobiologic spectrum of Schwannomas". Histol Histopathol. 18 (3): 925–34. PMID 12792904.
- ↑ "Libre Pathology schwannoma acoustic neuroma subtypes".