Osteosarcoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]

Overview

Osteosarcomas may be classified into several subtypes based on differentiation, location within the bone, and histological variants.

Classification

Osteosarcomas may be classified into several subtypes based on differentiation, location within the bone, and histological variants:

Intramedullary:

• Conventional high-grade
• Telangiectatic osteosarcoma
• Low-grade osteosarcoma
• Small cell osteosarcoma
• Osteosarcomatosis
• Gnathic osteosarcoma

Surface:

• Intracortical osteosarcoma
• Parosteal osteosarcoma
• Periosteal osteosarcoma
• High-grade osteosarcoma

Extraskeletal:

• Extraskeletal osteosarcoma