Meningioma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343 }} </ref> | Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.<ref name="wiki">Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015</ref><ref name="Canada">Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015</ref><ref name="pmid20821343">{{cite journal| author=Wiemels J, Wrensch M, Claus EB| title=Epidemiology and etiology of meningioma. | journal=J Neurooncol | year= 2010 | volume= 99 | issue= 3 | pages= 307-14 | pmid=20821343 | doi=10.1007/s11060-010-0386-3 | pmc=PMC2945461 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20821343 }} </ref> | ||
==Risk Factors== | |||
The table below lists the risk factors for multiple myeloma: | |||
{| {{table}} | |||
| align="center" style="background:#4479BA;"|'''Risk Factor''' | |||
| align="center" style="background:#4479BA;"|'''Description''' | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Age'''|| style="padding: 5px 5px; background: #F5F5F5;" |The chance to develop multiple myeloma increases as patients get older, where only 1% of multiple myeloma cases are diagnosed in patients younger than 35 years.<ref name="press">Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015</ref><ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Race'''|| style="padding: 5px 5px; background: #F5F5F5;" |African American and Native Pacific Islanders descents are at increased risk of developing multiple myeloma.<ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref><ref>Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Gender'''|| style="padding: 5px 5px; background: #F5F5F5;" |Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 2 to 1.<ref name="radio">Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015</ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Having other plasma cell diseases'''|| style="padding: 5px 5px; background: #F5F5F5;" |Patients with other [[plasma cell]] diseases such as [[monoclonal gammopathy of undetermined significance]] develop multiple myeloma later in their lives.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit§ion=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Family history'''|| style="padding: 5px 5px; background: #F5F5F5;" |A familial predisposition to myeloma exists due to [[hyperphosphorylation]] of specific proteins that may contribute to a higher rates of multiple myeloma in certain groups.<ref name="Bourguet-1985">{{Cite journal | last1 = Bourguet | first1 = CC. | last2 = Grufferman | first2 = S. | last3 = Delzell | first3 = E. | last4 = DeLong | first4 = ER. | last5 = Cohen | first5 = HJ. | title = Multiple myeloma and family history of cancer. A case-control study. | journal = Cancer | volume = 56 | issue = 8 | pages = 2133-9 | month = Oct | year = 1985 | doi = | PMID = 4027940 }}</ref><ref name="wiki">Multiple myeloma. Wikipedia (2015)https://en.wikipedia.org/wiki/Multiple_myeloma#Pathophysiology Accessed on September, 20th 2015</ref><ref name="pmid23926460">{{cite journal| author=Koura DT, Langston AA| title=Inherited predisposition to multiple myeloma. | journal=Ther Adv Hematol | year= 2013 | volume= 4 | issue= 4 | pages= 291-7 | pmid=23926460 | doi=10.1177/2040620713485375 | pmc=PMC3734900 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23926460 }} </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Obesity'''|| style="padding: 5px 5px; background: #F5F5F5;" | Being overweight increases a person's risk of developing multiple myeloma.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit§ion=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Workplace exposures'''|| style="padding: 5px 5px; background: #F5F5F5;" |Petroleum workers and farmers tend to have higher incidence of multiple myeloma relative to other occupations.<ref name="Gallagher-1983">{{Cite journal | last1 = Gallagher | first1 = RP. | last2 = Spinelli | first2 = JJ. | last3 = Elwood | first3 = JM. | last4 = Skippen | first4 = DH. | title = Allergies and agricultural exposure as risk factors for multiple myeloma. | journal = Br J Cancer | volume = 48 | issue = 6 | pages = 853-7 | month = Dec | year = 1983 | doi = | PMID = 6652026 }}</ref><ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit§ion=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | '''Radiation'''|| style="padding: 5px 5px; background: #F5F5F5;" | Areas with previous history of atoms bombs or nuclear accidents had higher risk of multiple myeloma due to increased rate of radiation exposure.<ref name="mediline">Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit§ion=2 Accessed on Septmeber, 20th 2015 </ref><ref name="american">Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015</ref> | |||
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Revision as of 18:01, 25 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Common risk factors in the development of meningioma are history of radiation treatment, inherited nervous system disorder, and female gender.[1][2][3]
Risk Factors
The table below lists the risk factors for multiple myeloma:
| Risk Factor | Description |
| Age | The chance to develop multiple myeloma increases as patients get older, where only 1% of multiple myeloma cases are diagnosed in patients younger than 35 years.[4][5][6] |
| Race | African American and Native Pacific Islanders descents are at increased risk of developing multiple myeloma.[1][6][7] |
| Gender | Males are more commonly affected with multiple myeloma than females. The male to female ratio is approximately 2 to 1.[5][6] |
| Having other plasma cell diseases | Patients with other plasma cell diseases such as monoclonal gammopathy of undetermined significance develop multiple myeloma later in their lives.[8][6] |
| Family history | A familial predisposition to myeloma exists due to hyperphosphorylation of specific proteins that may contribute to a higher rates of multiple myeloma in certain groups.[9][1][10][6] |
| Obesity | Being overweight increases a person's risk of developing multiple myeloma.[8][6] |
| Workplace exposures | Petroleum workers and farmers tend to have higher incidence of multiple myeloma relative to other occupations.[11][8][6] |
| Radiation | Areas with previous history of atoms bombs or nuclear accidents had higher risk of multiple myeloma due to increased rate of radiation exposure.[8][6] |
- Radiation treatment: Clinical data suggests that head radiation therapy increase the risk of developing meningioma.
- An inherited nervous system disorder: Studies show the rare disorder neurofibromatosis type 2 increases the risk of meningioma and other brain tumors.
- Female hormones: As a tumor common in women than men, doctors believe that female hormones may play an important role in developing meningioma.
References
- ↑ 1.0 1.1 1.2 Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma#Signs_and_symptoms Accessed on September, 25th 2015
- ↑ Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/risks/?region=mb Accessed on September, 25th 2015
- ↑ Wiemels J, Wrensch M, Claus EB (2010). "Epidemiology and etiology of meningioma". J Neurooncol. 99 (3): 307–14. doi:10.1007/s11060-010-0386-3. PMC 2945461. PMID 20821343.
- ↑ Press Releases. Compugen (2015)http://www.cgen.com/media-center/press-releases/-314 Accessed on September, 20th 2015
- ↑ 5.0 5.1 Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Multiple myeloma. The American Cancer Society (2015) http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-risk-factors Accessed on September, 20 2015
- ↑ Seer stat fact sheet. National cancer institute (2015)http://seer.cancer.gov/statfacts/html/mulmy.html Accessed on September, 20th 2015
- ↑ 8.0 8.1 8.2 8.3 Multiple myeloma. MedlinePlus (2015)http://www.wikidoc.org/index.php?title=Multiple_myeloma_risk_factors&action=edit§ion=2 Accessed on Septmeber, 20th 2015
- ↑ Bourguet, CC.; Grufferman, S.; Delzell, E.; DeLong, ER.; Cohen, HJ. (1985). "Multiple myeloma and family history of cancer. A case-control study". Cancer. 56 (8): 2133–9. PMID 4027940. Unknown parameter
|month=ignored (help) - ↑ Koura DT, Langston AA (2013). "Inherited predisposition to multiple myeloma". Ther Adv Hematol. 4 (4): 291–7. doi:10.1177/2040620713485375. PMC 3734900. PMID 23926460.
- ↑ Gallagher, RP.; Spinelli, JJ.; Elwood, JM.; Skippen, DH. (1983). "Allergies and agricultural exposure as risk factors for multiple myeloma". Br J Cancer. 48 (6): 853–7. PMID 6652026. Unknown parameter
|month=ignored (help)