Mediastinitis natural history, complications and prognosis: Difference between revisions
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{{Mediastinitis}} | {{Mediastinitis}} | ||
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==Overview== | ==Overview== | ||
If left untreated, fibrosing mediastinitis may progress into [[sepsis]] and subsequently, death.<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.<ref name="pmid23351519">{{cite journal| author=Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A| title=[Mediastinitis]. | journal=Arch Bronconeumol | year= 2011 | volume= 47 Suppl 8 | issue= | pages= 32-6 | pmid=23351519 | doi=10.1016/S0300-2896(11)70065-5 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23351519 }} </ref> The most severe complication is sepsis, which could result in death. | |||
==Natural History== | ==Natural History== | ||
If left untreated, fibrosing mediastinitis may progress into [[sepsis]] and subsequently, death.<ref> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> | If left untreated, fibrosing mediastinitis may progress into [[sepsis]] and subsequently, death.<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.<ref name="pmid23351519">{{cite journal| author=Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A| title=[Mediastinitis]. | journal=Arch Bronconeumol | year= 2011 | volume= 47 Suppl 8 | issue= | pages= 32-6 | pmid=23351519 | doi=10.1016/S0300-2896(11)70065-5 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23351519 }} </ref> | ||
==Complications== | ==Complications== | ||
[[ | Common complications include the following:<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> <Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015</ref> | ||
*Development of [[sepsis]] | |||
*Spread of the [[infection]] to the: | *Spread of the [[infection]] to the: | ||
**[[Bloodstream]] | **[[Bloodstream]] | ||
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**[[Heart]] | **[[Heart]] | ||
**[[Lungs]] | **[[Lungs]] | ||
*[[Scarring]] | |||
*[[Pneumonia]] | |||
==Prognosis== | ==Prognosis== | ||
Revision as of 18:44, 25 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
If left untreated, fibrosing mediastinitis may progress into sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.[2] The most severe complication is sepsis, which could result in death.
Natural History
If left untreated, fibrosing mediastinitis may progress into sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.[2]
Complications
Common complications include the following:[1] <Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015</ref>
Prognosis
Mediastinitis may be treated with antibiotics, depending on the severity of the infection. The presence of mediastinitis among patients following chest surgery is observed to have a particularly poor prognosis; there is a serious risk of death.
References
- ↑ 1.0 1.1 1.2 Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.
- ↑ 2.0 2.1 Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A (2011). "[Mediastinitis]". Arch Bronconeumol. 47 Suppl 8: 32–6. doi:10.1016/S0300-2896(11)70065-5. PMID 23351519.