Osteosarcoma classification: Difference between revisions
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Osteosarcomas may be classified into several subtypes based on differentiation, location within the bone, and histological variants. | Osteosarcomas may be classified into several subtypes based on differentiation, location within the bone, and histological variants. | ||
==Classification | ==Classification== | ||
The World Health Organization’s histologic classification of bone tumors separates the osteosarcomas into central (medullary) and surface (peripheral) tumors and recognizes a number of subtypes within each group.<ref>Osteosarcoma. National cancer institute.http://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq#section/_8</ref> | |||
'''Central (medullary) tumors: ''' | |||
*Conventional central osteosarcomas. | |||
*Telangiectatic osteosarcomas. | |||
*Intraosseous well-differentiated (low-grade) osteosarcomas. | |||
*Small-cell osteosarcomas. | |||
'''Surface (peripheral) tumors: ''' | |||
*Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcomas. | |||
*Periosteal osteosarcoma: Low-grade to intermediate-grade osteosarcomas. | |||
*High-grade surface osteosarcomas. | |||
'''Extraskeletal:''' | '''Extraskeletal:''' | ||
*Extraskeletal | *Extraskeletal osteosarcomas. | ||
==References== | ==References== | ||
Revision as of 14:16, 30 September 2015
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Osteosarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Osteosarcoma classification On the Web |
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American Roentgen Ray Society Images of Osteosarcoma classification |
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Risk calculators and risk factors for Osteosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Osteosarcomas may be classified into several subtypes based on differentiation, location within the bone, and histological variants.
Classification
The World Health Organization’s histologic classification of bone tumors separates the osteosarcomas into central (medullary) and surface (peripheral) tumors and recognizes a number of subtypes within each group.[1]
Central (medullary) tumors:
- Conventional central osteosarcomas.
- Telangiectatic osteosarcomas.
- Intraosseous well-differentiated (low-grade) osteosarcomas.
- Small-cell osteosarcomas.
Surface (peripheral) tumors:
- Parosteal (juxtacortical) well-differentiated (low-grade) osteosarcomas.
- Periosteal osteosarcoma: Low-grade to intermediate-grade osteosarcomas.
- High-grade surface osteosarcomas.
Extraskeletal:
- Extraskeletal osteosarcomas.
References
- ↑ Osteosarcoma. National cancer institute.http://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq#section/_8