Carcinoid syndrome causes: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 6: | Line 6: | ||
==Causes== | ==Causes== | ||
* | Common causes of carcinoid syndrome include: | ||
. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq | *Genetic disorders | ||
**[[Multiple endocrine neoplasia type 1]] | |||
**[[Neurofibromatosis type 1]].<ref>Molecular genetics. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq</ref> | |||
*In sporadic gastrointestinal carcinoids, numerous chromosomal imbalances have been found by comparative genome hybridization analysis. Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common. | **Carcinoids associated with [[multiple endocrine neoplasia type 1]] appear to be of [[foregut]] origin. | ||
** Carcinoids in patients with [[neurofibromatosis type 1]] appear to arise primarily in the periampullary region. | |||
*In sporadic gastrointestinal carcinoids, numerous chromosomal imbalances have been found by comparative genome hybridization analysis. | |||
**Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common. | |||
==References== | ==References== | ||
Revision as of 15:06, 29 September 2015
|
Carcinoid syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Carcinoid syndrome causes On the Web |
|
American Roentgen Ray Society Images of Carcinoid syndrome causes |
|
Risk calculators and risk factors for Carcinoid syndrome causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Majority of the cases of gastrointestinal carcinoid are sporadic, however gastrointestinal carcinoid is associated with mutations in MEN1 and NF1 genes.
Causes
Common causes of carcinoid syndrome include:
- Genetic disorders
- Multiple endocrine neoplasia type 1
- Neurofibromatosis type 1.[1]
- Carcinoids associated with multiple endocrine neoplasia type 1 appear to be of foregut origin.
- Carcinoids in patients with neurofibromatosis type 1 appear to arise primarily in the periampullary region.
- In sporadic gastrointestinal carcinoids, numerous chromosomal imbalances have been found by comparative genome hybridization analysis.
- Gains involving chromosomes 5, 14, 17 (especially 17q), and 19 and losses involving chromosomes 11 (especially 11q) and 18 appear to be the most common.
References
- ↑ Molecular genetics. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq