Burkitt's lymphoma classification: Difference between revisions
No edit summary |
No edit summary |
||
| Line 32: | Line 32: | ||
* Sometimes associated with the [[Epstein-Barr virus]], but in many cases this virus is not present | * Sometimes associated with the [[Epstein-Barr virus]], but in many cases this virus is not present | ||
* [[Non-Hodgkin's lymphoma]], which includes Burkitt's, accounts for 30-50% of childhood lymphoma | * [[Non-Hodgkin's lymphoma]], which includes Burkitt's, accounts for 30-50% of childhood lymphoma | ||
* | * Ileo-cecal region is the common site of involvement | ||
* Most often starts in the abdomen, but can also start in the ovaries, testicles, kidneys or other organs | * Most often starts in the abdomen, but can also start in the ovaries, testicles, kidneys or other organs | ||
* Jaw is less commonly involved, comparing with the endemic variant | * Jaw is less commonly involved, comparing with the endemic variant | ||
| Line 39: | Line 39: | ||
| style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Immunodeficiency-associated Burkitt's lymphoma''' | | style="text-align: center; padding: 5px 5px; background: #F5F5F5;" | '''Immunodeficiency-associated Burkitt's lymphoma''' | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
* Tends to occur in people with weakened immune systems, typically those with [[HIV]] infection | * Tends to occur in people with weakened [[immune systems]], typically those with [[HIV]] infection | ||
* Incidence | * Incidence appears to be dropping because of [[antiretroviral therapy]] | ||
* About 30–40% of cases are associated with the Epstein-Barr virus | * About 30–40% of cases are associated with the Epstein-Barr virus | ||
|} | |} | ||
Revision as of 13:32, 29 September 2015
|
Burkitt's lymphoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Burkitt's lymphoma classification On the Web |
|
American Roentgen Ray Society Images of Burkitt's lymphoma classification |
|
Risk calculators and risk factors for Burkitt's lymphoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Burkitt's lymphoma may be classified into 3 clinical variants: endemic Burkitt's lymphoma, sporadic Burkitt's lymphoma, and immunodeficiency-associated Burkitt's lymphoma.
Classification
Burkitt's lymphoma may be classified into 3 clinical variants:[1]
- Endemic Burkitt's lymphoma
- Sporadic Burkitt's lymphoma
- Immunodeficiency-associated Burkitt's lymphoma
By morphology (i.e. microscopic appearance) or immunophenotype, it is almost impossible to differentiate these three clinical variants. Immunodeficiency-associated Burkitt's lymphoma may demonstrate more plasmacytic appearance or more pleomorphism, but these features are not specific.
| Name | Description |
|---|---|
| Endemic Burkitt's lymphoma
(African Burkitt's lymphoma) |
|
| Sporadic Burkitt's lymphoma
(Non-African or Non-endemic Burkitt's lymphoma) |
|
| Immunodeficiency-associated Burkitt's lymphoma |
|
References
- ↑ Burkitt lymphoma. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/burkitt-lymphoma/?region=on Accessed on September 29, 2015