Medulloblastoma staging: Difference between revisions

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Revision as of 21:03, 29 September 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

The staging of medulloblastoma is based on the TNM clinical classification.^[1]^[2]^[3]

TNM Classification of Medulloblastoma

The staging of medulloblastoma is based on the TNM clinical classification demonstrated below.^[1]^[2]^[3]

T: Primary Tumor

T	Description
TX	Primary tumor cannot be assessed
T0	There is no evidence of primary tumor
T1	Tumor size <3 cm in diameter
T2	Tumor size ≥3 cm in diameter with no evidence of extension
T3a	Tumor size >3 cm in diameter with extension into aqueduct of Sylvius or foramen of Luschka
T3b	Tumor size >3 cm in diameter with definite spread into the brain stem
T4	Tumor size >3 cm in diameter with extension past aqueduct of Sylvius or down past foramen magnum

N:Regional Lymph Nodes

An N classification cannot be applied to medulloblastoma.

M: Distant Metastasis

T	Description
M0	No evidence of metastasis
M1	Microscopic tumor cells presemt in the cerebrospinal fluid
M2	Gross nodular seeding present intracranially beyond the primary site
M3	Gross nodular seeding present in the spinal subarachnoid space
M4	Metastasis present outside the cerebrospinal axis

References

↑ ^1.0 ^1.1 Szuwart U, Bennefeld H, Behr H (1989). "Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors". Neurosurg Rev. 12 (3): 233–8. PMID 2812355.
↑ ^2.0 ^2.1 Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging
↑ ^3.0 ^3.1 All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging

[pmid2812355-1] 1.0 ^1.1 Szuwart U, Bennefeld H, Behr H (1989). "Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors". Neurosurg Rev. 12 (3): 233–8. PMID 2812355.

[R-2] 2.0 ^2.1 Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging

[WB-3] 3.0 ^3.1 All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging

[1]

[2]

[3]

@@ Line 4: / Line 4: @@
 ==Overview==
-The staging of medulloblastoma is based on the TNM clinical classification.<ref name="pmid2812355">{{cite journal| author=Szuwart U, Bennefeld H, Behr H| title=Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors. | journal=Neurosurg Rev | year= 1989 | volume= 12 | issue= 3 | pages= 233-8 | pmid=2812355 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2812355  }} </ref><ref>Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref><ref>All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref>
+The staging of medulloblastoma is based on the TNM clinical classification.<ref name="pmid2812355">{{cite journal| author=Szuwart U, Bennefeld H, Behr H| title=Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors. | journal=Neurosurg Rev | year= 1989 | volume= 12 | issue= 3 | pages= 233-8 | pmid=2812355 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2812355  }} </ref><ref name="R">Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref><ref name="WB">All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref>
 ==TNM Classification of Medulloblastoma==
-* The staging of medulloblastoma is based on the TNM clinical classification demonstrated below<ref name="pmid2812355">{{cite journal| author=Szuwart U, Bennefeld H, Behr H| title=Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors. | journal=Neurosurg Rev | year= 1989 | volume= 12 | issue= 3 | pages= 233-8 | pmid=2812355 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2812355  }} </ref><ref>Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref><ref>All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref>
+* The staging of medulloblastoma is based on the TNM clinical classification demonstrated below.<ref name="pmid2812355">{{cite journal| author=Szuwart U, Bennefeld H, Behr H| title=Classification of gliomas and medulloblastomas using the new TNM system for cerebral tumors. | journal=Neurosurg Rev | year= 1989 | volume= 12 | issue= 3 | pages= 233-8 | pmid=2812355 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2812355  }} </ref><ref name="R">Radiation Oncology/Medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref><ref name="WB">All about medulloblastoma. Wikibooks(2015) https://en.wikibooks.org/wiki/Radiation_Oncology/Medulloblastoma/Staging Accessed on September, 28th 2015/Staging</ref>
 ===T: Primary Tumor===
@@ Line 14: / Line 14: @@
 | style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''T'''||style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF" align=center |'''Description'''
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |TX || style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Primary tumor cannot be assessed
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''TX''' || style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Primary tumor cannot be assessed
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T0 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |There is no evidence of primary tumor
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T0''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |There is no evidence of primary tumor
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T1 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size <3 cm in diameter
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T1''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size <3 cm in diameter
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T2 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size ≥3 cm in diameter with no evidence of extension
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T2''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size ≥3 cm in diameter with no evidence of extension
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T3a ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size >3 cm in diameter with extension into aqueduct of Sylvius or foramen of Luschka
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T3a''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size >3 cm in diameter with extension into aqueduct of Sylvius or foramen of Luschka
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T3b ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size >3 cm in diameter with definite spread into the brain stem
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T3b''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Tumor size >3 cm in diameter with definite spread into the brain stem
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |T4 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Tumor size >3 cm in diameter with extension past aqueduct of Sylvius or down past foramen magnum
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''T4''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Tumor size >3 cm in diameter with extension past aqueduct of Sylvius or down past foramen magnum
 |}
@@ Line 51: / Line 51: @@
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |M0||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |No evidence of metastasis
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''M0'''||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |No evidence of metastasis
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |M1 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Microscopic tumor cells presemt in the cerebrospinal fluid
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''M1''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Microscopic tumor cells presemt in the cerebrospinal fluid
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |M2 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Gross nodular seeding present intracranially beyond the primary site
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''M2''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left |Gross nodular seeding present intracranially beyond the primary site
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |M3 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Gross nodular seeding present in the spinal subarachnoid space
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''M3''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Gross nodular seeding present in the spinal subarachnoid space
 |-
-|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |M4 ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Metastasis present outside the cerebrospinal axis
+|style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=center |'''M4''' ||style="font-size: 100; padding: 0 5px; background: #F5F5F5" align=left | Metastasis present outside the cerebrospinal axis
 |}
-==Classification of Medulloblastoma by Staging==
 ==References==