Medulloblastoma epidemiology and demographics: Difference between revisions
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===Prevalance=== | ===Prevalance=== | ||
===Incidence=== | ===Incidence=== | ||
* The overall age adjusted incidence rate of medulloblastoma is approximately 0.71 per 100,000 individuals in the United States.<ref name="pmid23925828">{{cite journal| author=McKean-Cowdin R, Razavi P, Barrington-Trimis J, Baldwin RT, Asgharzadeh S, Cockburn M et al.| title=Trends in childhood brain tumor incidence, 1973-2009. | journal=J Neurooncol | year= 2013 | volume= 115 | issue= 2 | pages= 153-60 | pmid=23925828 | doi=10.1007/s11060-013-1212-5 | pmc=PMC4056769 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23925828 }} </ref> | |||
Medulloblastoma is the most common malignant brain tumor, comprising 14.5% of newly diagnosed cases.<ref name="seer">James G. Gurney, Malcolm A. Smith, Greta R. Bunin, [http://seer.cancer.gov/publications/childhood/cns.pdf CNS and Miscellaneous Intracranial and Intraspinal Neoplasms], SEER Pediatric Monograph, National Cancer Institute</ref> | Medulloblastoma is the most common malignant brain tumor, comprising 14.5% of newly diagnosed cases.<ref name="seer">James G. Gurney, Malcolm A. Smith, Greta R. Bunin, [http://seer.cancer.gov/publications/childhood/cns.pdf CNS and Miscellaneous Intracranial and Intraspinal Neoplasms], SEER Pediatric Monograph, National Cancer Institute</ref> | ||
In adults, medulloblastoma is rare, comprising less than 2% of CNS malignancies.<ref>[http://cbtrus.org/2005-2006/tables/2006.table12.pdf Selected Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates], Central Brain Tumor Registry of the United States, 1998-2002.</ref> | In adults, medulloblastoma is rare, comprising less than 2% of CNS malignancies.<ref>[http://cbtrus.org/2005-2006/tables/2006.table12.pdf Selected Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates], Central Brain Tumor Registry of the United States, 1998-2002.</ref> | ||
Medulloblastoma and other PNET tumors are more prevalent in younger children than older children. | * Medulloblastoma and other PNET tumors are more prevalent in younger children than older children. | ||
:* 40% of medulloblastoma patients are diagnosed before the age of 5 | |||
:* 31% are between the ages of 5 and 9 | |||
:* 18.3% are between the ages of 10 and 14 | |||
18.3% are between the ages of 10 and 14 | |||
2.7% are between the ages of 15 and 19. <ref>[http://cbtrus.org/2005-2006/tables/2006.table15.pdf Selected Childhood Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates], Central Brain Tumor Registry of the United States, 1998-2002.</ref> | 2.7% are between the ages of 15 and 19. <ref>[http://cbtrus.org/2005-2006/tables/2006.table15.pdf Selected Childhood Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates], Central Brain Tumor Registry of the United States, 1998-2002.</ref> | ||
Revision as of 17:58, 30 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Epidemiology and Demographics
Prevalance
Incidence
- The overall age adjusted incidence rate of medulloblastoma is approximately 0.71 per 100,000 individuals in the United States.[1]
Medulloblastoma is the most common malignant brain tumor, comprising 14.5% of newly diagnosed cases.[2]
In adults, medulloblastoma is rare, comprising less than 2% of CNS malignancies.[3]
- Medulloblastoma and other PNET tumors are more prevalent in younger children than older children.
- 40% of medulloblastoma patients are diagnosed before the age of 5
- 31% are between the ages of 5 and 9
- 18.3% are between the ages of 10 and 14
2.7% are between the ages of 15 and 19. [4]
Age
Gender
Race
References
- ↑ McKean-Cowdin R, Razavi P, Barrington-Trimis J, Baldwin RT, Asgharzadeh S, Cockburn M; et al. (2013). "Trends in childhood brain tumor incidence, 1973-2009". J Neurooncol. 115 (2): 153–60. doi:10.1007/s11060-013-1212-5. PMC 4056769. PMID 23925828.
- ↑ James G. Gurney, Malcolm A. Smith, Greta R. Bunin, CNS and Miscellaneous Intracranial and Intraspinal Neoplasms, SEER Pediatric Monograph, National Cancer Institute
- ↑ Selected Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates, Central Brain Tumor Registry of the United States, 1998-2002.
- ↑ Selected Childhood Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates, Central Brain Tumor Registry of the United States, 1998-2002.