Acoustic neuroma classification: Difference between revisions
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**Melanotic schwannoma: It may be confused with [[melanoma]]. [[File:Psammomatous_melanotic_schwannoma.jpg|thumb|none|800px|Psammomatous melanotic schwannoma]] | **Melanotic schwannoma: It may be confused with [[melanoma]]. [[File:Psammomatous_melanotic_schwannoma.jpg|thumb|none|800px|Psammomatous melanotic schwannoma]] | ||
It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). | It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). | ||
The Carney complex, also known as Carney syndrome, NAME syndrome and LAMB syndrome, is a bunch of things that occur together due to some [[genetic]] problem. | The [[Carney complex]], also known as [[Carney syndrome]], NAME syndrome and LAMB syndrome, is a bunch of things that occur together due to some [[genetic]] problem. | ||
It consists of:<ref>{{Cite web | title =Libre Pathology schwannoma acoustic neuroma subtypes| url =http://librepathology.org/wiki/index.php/Schwannoma }}</ref> | It consists of:<ref>{{Cite web | title =Libre Pathology schwannoma acoustic neuroma subtypes| url =http://librepathology.org/wiki/index.php/Schwannoma }}</ref> | ||
*[[Cutaneous]] lentigines | *[[Cutaneous]] lentigines |
Revision as of 19:45, 1 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Acoustic neuroma may be classified into three subtypes based on MRI scan, and into four subtypes based on microscopic histopathology.[1]
Classification
Based on the MRI scan, acoustic neuromas can be classified into three subtypes:
- Entirely intracanalicular: The entire tumor is completely within the bony canal
- Intracranial extension without brain stem distortion
- Intracranial extension with brain stem distortion
Based on microscopic histopathology, acoustic neuroma can be classified into four subtypes:[2]
- Conventional schwannoma
- Cellular schwannoma
- Plexiform schwannoma
- Melanotic schwannoma
It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). The Carney complex, also known as Carney syndrome, NAME syndrome and LAMB syndrome, is a bunch of things that occur together due to some genetic problem. It consists of:[3]
- Cutaneous lentigines
- Myxomas (skin (subcutaneous), subcutanous, heart)
- Endocrine neoplasms
References
- ↑ "Libre Pathology schwannoma acoustic neuroma subtypes".
- ↑ Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM (2003). "The pathobiologic spectrum of Schwannomas". Histol Histopathol. 18 (3): 925–34. PMID 12792904.
- ↑ "Libre Pathology schwannoma acoustic neuroma subtypes".