Angiomyolipoma other diagnostic studies: Difference between revisions
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Biopsy findings of angiomyolipoma include: | Biopsy findings of angiomyolipoma include: | ||
===Microscopic Features=== | ===Microscopic Features=== | ||
Microscopic features of angiomyolipoma are: | Microscopic features of angiomyolipoma are:<ref name=pmid15584043>{{Cite journal | last1 = Crapanzano | first1 = JP. | title = Fine-needle aspiration of renal angiomyolipoma: cytological findings and diagnostic pitfalls in a series of five cases. | journal = Diagn Cytopathol | volume = 32 | issue = 1 | pages = 53-7 | month = Jan | year = 2005 | doi = 10.1002/dc.20179 | PMID = 15584043 }}</ref> | ||
*[[Smooth muscle]] | *[[Smooth muscle]] | ||
*Adipose tissue | *Adipose tissue | ||
*Abundant [[blood vessel]]s | *Abundant [[blood vessel]]s | ||
<gallery> | <gallery> | ||
Revision as of 02:01, 2 October 2015
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Angiomyolipoma Microchapters |
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Angiomyolipoma other diagnostic studies On the Web |
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American Roentgen Ray Society Images of Angiomyolipoma other diagnostic studies |
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Risk calculators and risk factors for Angiomyolipoma other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
CT guided biopsy is diagnostic of angiomyolipoma.
Biopsy Findings
Biopsy findings of angiomyolipoma include:
Microscopic Features
Microscopic features of angiomyolipoma are:[1]
- Smooth muscle
- Adipose tissue
- Abundant blood vessels
-
![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/images/a/a3/Renal_angiomyolipoma_%281%29.jpg)
Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]
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![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/images/b/be/Renal_angiomyolipoma_%282%29.jpg)
Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]
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![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/images/d/d2/Renal_angiomyolipoma_%283%29.jpg)
Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]
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![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. HMB-45 immunostain.[2]](/images/0/07/Renal_angiomyolipoma_%284%29_HMB-45_immunostain.JPG)
Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. HMB-45 immunostain.[2]
![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/index.php/File:Renal_angiomyolipoma_(1).jpg)
![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/index.php/File:Renal_angiomyolipoma_(2).jpg)
![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. H & E stain.[2]](/index.php/File:Renal_angiomyolipoma_(3).jpg)
![Histopathologic image of renal angiomyolipoma. Nephrectomy specimen. HMB-45 immunostain.[2]](/index.php/File:Renal_angiomyolipoma_(4)_HMB-45_immunostain.JPG)
Cytologic
Cytologic features of angiomyolipoma include:[1]
Immunohistochemistry
Immunohistochemistry markers of angiomyolipoma include:
- Melanocytic markers positive[3]
- HMB-45 positive in all cases (15/15)[4]
- Melan A positive in ~87% of cases (13/15)
- Epithelial markers negative[3]
- EMA
- AE1/AE3
- SMA positive
- CD117 positive/negative
- Ki-67:[5]
- Epithelioid variant of angiomyolipoma positive
- Conventional angiomyolipoma negative
References
- ↑ 1.0 1.1 Crapanzano, JP. (2005). "Fine-needle aspiration of renal angiomyolipoma: cytological findings and diagnostic pitfalls in a series of five cases". Diagn Cytopathol. 32 (1): 53–7. doi:10.1002/dc.20179. PMID 15584043. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 2.2 2.3 http://librepathology.org/wiki/index.php/Angiomyolipoma
- ↑ 3.0 3.1 Template:Ref GUP
- ↑ Esheba, Gel S.; Esheba, Nel S. (2013). "Angiomyolipoma of the kidney: clinicopathological and immunohistochemical study". J Egypt Natl Canc Inst. 25 (3): 125–34. doi:10.1016/j.jnci.2013.05.002. PMID 23932749. Unknown parameter
|month=ignored (help) - ↑ Ooi, SM.; Vivian, JB.; Cohen, RJ. (2009). "The use of the Ki-67 marker in the pathological diagnosis of the epithelioid variant of renal angiomyolipoma". Int Urol Nephrol. 41 (3): 559–65. doi:10.1007/s11255-008-9473-1. PMID 18839327.