Medulloblastoma medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy== | ||
* The algorithm below summarize the management approach for medulloblastoma patients:<ref name="pmid22622599">{{cite journal| author=von Hoff K, Rutkowski S| title=Medulloblastoma. | journal=Curr Treat Options Neurol | year= 2012 | volume= 14 | issue= 4 | pages= 416-26 | pmid=22622599 | doi=10.1007/s11940-012-0183-8 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22622599 }} </ref> | |||
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{{Family tree | | | | A01 | | | |A01=<div style="width: 20em; padding:1em;">'''Maximal safe surgery'''</div>}} | |||
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{{Family tree | | | | B01 | | | |B01=<div style="width: 20em; padding:1em;">'''Histopathological analysis'''</div>}} | |||
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{{Family tree | | | | B01 | | | |B01=<div style="width: 20em; padding:1em;">'''Thorough staging'''</div>}} | |||
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{{Family tree | | | | B01 | | | |B01=<div style="width: 20em; padding:1em;">'''Optimal risk stratification'''</div>}} | |||
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{{Family tree | | | | B01 | | | |B01=<div style="width: 20em; padding:1em;">'''Radiotherapy and chemotherapy'''<br> | |||
'''according to the risk stratification criteria'''</div>}} | |||
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===Radiation Therapy=== | ===Radiation Therapy=== |
Revision as of 03:30, 2 October 2015
Medulloblastoma Microchapters |
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Medulloblastoma medical therapy On the Web |
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Risk calculators and risk factors for Medulloblastoma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Medical Therapy
- The algorithm below summarize the management approach for medulloblastoma patients:[1]
Maximal safe surgery | |||||||||||||||||||
Histopathological analysis | |||||||||||||||||||
Thorough staging | |||||||||||||||||||
Optimal risk stratification | |||||||||||||||||||
Radiotherapy and chemotherapy according to the risk stratification criteria | |||||||||||||||||||
Radiation Therapy
- Radiotherapy is the mainstay of treatment for medulloblastoma.[2]
- Radiotherapy for medulloblastoma must be started within 6 weeks following surgery.
- The main radiotherapy techniques used in the management of medulloblastoma patients include:
- Conventional radiotherapy technique
- Intensity modulated radiotherapy technique
- Three dimensional radiotherapy technique
- Three dimensional radiotherapy technique demonstrated better outcomes when compared to conventional and intensity modulated radiotherapy techniques.
- As medulloblastoma tends to spread along the cerebrospinal fluid, it is recommended to deliver a craniospinal irradiation with a boost to the posterior fossa.
Chemotherapy
References
- ↑ von Hoff K, Rutkowski S (2012). "Medulloblastoma". Curr Treat Options Neurol. 14 (4): 416–26. doi:10.1007/s11940-012-0183-8. PMID 22622599.
- ↑ Bartlett F, Kortmann R, Saran F (2013). "Medulloblastoma". Clin Oncol (R Coll Radiol). 25 (1): 36–45. doi:10.1016/j.clon.2012.09.008. PMID 23245832.