Pituitary adenoma pathophysiology: Difference between revisions
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:*Pituitary microadenomas are defined as adenomas less than 10 mm in size. | :*Pituitary microadenomas are defined as adenomas less than 10 mm in size. | ||
:*Most frequently diagnosed as a result of investigating hormonal imbalance. | :*Most frequently diagnosed as a result of investigating hormonal imbalance. | ||
:*They are confined to the [[sella]] and has no scope to produce mass effect related symptoms. | :*They are confined to the [[sella]] and has no scope to produce mass effect related symptoms. | ||
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Pituitary adenoma (1) GH production.jpg|Histopathological image of pituitary adenoma with GH production. Acidophilic cell type. Hematoxylin & esoin stain.<ref name=Wikipedia1> https://en.wikipedia.org/wiki/Pituitary_adenoma#/media/File:Pituitary_adenoma_%281%29_GH_production.jpg</ref> | |||
*'''''Macroadenoma<small><ref name=radio>Pituitary adenoma. Dr Amir Rezaee and Dr Yuranga Weerakkody. Radiopaedia.org 2015.http://radiopaedia.org/articles/pituitary-adenoma</ref></small>''''' | *'''''Macroadenoma<small><ref name=radio>Pituitary adenoma. Dr Amir Rezaee and Dr Yuranga Weerakkody. Radiopaedia.org 2015.http://radiopaedia.org/articles/pituitary-adenoma</ref></small>''''' | ||
:*Pituitary macroadenomas are the most common [[suprasellar]] mass in adults. | :*Pituitary macroadenomas are the most common [[suprasellar]] mass in adults. | ||
Revision as of 21:54, 2 October 2015
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Pituitary adenoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Pituitary adenoma pathophysiology On the Web |
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American Roentgen Ray Society Images of Pituitary adenoma pathophysiology |
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Risk calculators and risk factors for Pituitary adenoma pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
On gross pathology, a well circumscribed suprasellar mass is a characteristic finding of pituitary adenoma. On microscopic histopathological analysis, a monomorphic expansion of usually one cell type with lack of reticulin network among neoplastic cells is a characteristic finding of pituitary adenoma.
Pathophysiology
- Pathological feature
- The radioanatomical classification places adenomas into 1 of 4 grades:
- Stage I involve microadenomas (<1 cm) without sellar expansion.
- Stage II involve macroadenomas (≥1 cm) and may extend above the sella.
- Stage III involve macroadenomas with enlargement and invasion of the floor or suprasellar extension.
- Stage IV involve macroadenomas that cause destruction of the sella.
- Microadenoma[1]
- Pituitary microadenomas are defined as adenomas less than 10 mm in size.
- Most frequently diagnosed as a result of investigating hormonal imbalance.
- They are confined to the sella and has no scope to produce mass effect related symptoms.
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![Histopathological image of pituitary adenoma with GH production. Acidophilic cell type. Hematoxylin & esoin stain.[2]](/images/9/9d/Pituitary_adenoma_%281%29_GH_production.jpg)
Histopathological image of pituitary adenoma with GH production. Acidophilic cell type. Hematoxylin & esoin stain.[2]
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![Histopathological image of nonfunctioning pituitary adenoma. Hematoxylin & eosin stain.[3]](/images/d/de/Nonfunctioning_pituitary_adenoma_%281%29.jpg)
Histopathological image of nonfunctioning pituitary adenoma. Hematoxylin & eosin stain.[3]
![Histopathological image of pituitary adenoma with GH production. Acidophilic cell type. Hematoxylin & esoin stain.[2]](/index.php/File:Pituitary_adenoma_(1)_GH_production.jpg)
![Histopathological image of nonfunctioning pituitary adenoma. Hematoxylin & eosin stain.[3]](/index.php/File:Nonfunctioning_pituitary_adenoma_(1).jpg)
References
- ↑ pituitary micro adenoma Dr Amir Rezaee and Dr Frank Gaillard. 2015 http://radiopaedia.org/articles/pituitary-microadenoma
- ↑ https://en.wikipedia.org/wiki/Pituitary_adenoma#/media/File:Pituitary_adenoma_%281%29_GH_production.jpg
- ↑ https://en.wikipedia.org/wiki/Pituitary_adenoma#/media/File:Nonfunctioning_pituitary_adenoma_%281%29.jpg
