Thyroid adenoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
==Classification== | ==Classification== | ||
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{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= Thyroid adenoma}} | |||
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{{Familytree|boxstyle=background: #E0FFFF;| | B01 | | B02 | | B03 | | | | | | B04 | | B05 | | B06 | | | | | | | | | | | | | | | | |B01=Microfollicular adenoma|B02=Macrofollicular adenoma|B03=Atypical Embryonal adenoma|B04=Hürthle cell adenoma|B05=Hyalinizing trabecular adenoma|B06=Papillary adenoma}} | |||
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Almost all [[thyroid]] adenomas are follicular adenomas.<ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1117 |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref> [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types: | Almost all [[thyroid]] adenomas are follicular adenomas.<ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1117 |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref> [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types: | ||
*Fetal (microfollicular) - these have the potential for microinvasion.<ref name=Kelley2008/> These consist of small, closely packed follicles lined with epithelium.<ref>[http://medical-dictionary.thefreedictionary.com/microfollicular+adenoma TheFreeDictionary > microfollicular adenoma] Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007</ref> | *Fetal (microfollicular) - these have the potential for microinvasion.<ref name=Kelley2008/> These consist of small, closely packed follicles lined with epithelium.<ref>[http://medical-dictionary.thefreedictionary.com/microfollicular+adenoma TheFreeDictionary > microfollicular adenoma] Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Classification
| Thyroid adenoma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Microfollicular adenoma | Macrofollicular adenoma | Atypical Embryonal adenoma | Hürthle cell adenoma | Hyalinizing trabecular adenoma | Papillary adenoma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Almost all thyroid adenomas are follicular adenomas.[1] Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.[2] Histopathologically, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types:
- Fetal (microfollicular) - these have the potential for microinvasion.[3] These consist of small, closely packed follicles lined with epithelium.[4]
- Colloid (macrofollicular) - these do not have any potential for microinvasion[3]
- Embryonal (atypical) - have the potential for microinvasion.[3]
- Hürthle cell adenoma (oxyphil or oncocytic tumor) - have the potential for microinvasion.[3]
- Hyalinizing trabecular adenoma[5]
Papillary adenomas are very rare.[3]
Reference
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. p. 1117. ISBN 0-7216-0187-1.
- ↑ "Endocrine Pathology". Retrieved 2009-05-08.
- ↑ 3.0 3.1 3.2 3.3 3.4 emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008
- ↑ TheFreeDictionary > microfollicular adenoma Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007
- ↑ Ünlütürk, U; Karaveli, G; Sak, S. D.; Erdoğan, M. F. (2011). "Hyalinizing trabecular tumor in a background of lymphocytic thyroiditis: A challenging neoplasm of the thyroid". Endocrine Practice. 17 (6): e140–3. doi:10.4158/EP11138.CR. PMID 21940281.