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==Overview==
==Overview==
==Classification==
==Classification==
* Thyroid adenomas are classified into 2 subtype: follicular adenoma and others.  
* Thyroid adenomas are classified into 2 subtype: [[Follicular thyroid adenoma|follicular adenoma]] and others.  
* Others include papillary adenoma which is very rare.<ref name=Kelley2008>[http://emedicine.medscape.com/article/850823-overview#aw2aab6b4 emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules] By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008</ref> Almost all [[thyroid]] adenomas are follicular adenomas.<ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1117 |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref>  
* Almost all [[thyroid]] adenomas are follicular adenomas.<ref name="isbn0-7216-0187-1">{{cite book |author=Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. |title=Robbins and Cotran pathologic basis of disease |publisher=Elsevier Saunders |location=St. Louis, Mo |year=2005 |pages=1117 |isbn=0-7216-0187-1 |oclc= |doi= |accessdate=}}</ref> Others include papillary adenoma which is very rare.<ref name=Kelley2008>[http://emedicine.medscape.com/article/850823-overview#aw2aab6b4 emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules] By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008</ref>  
* Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref>  
* Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.<ref name="urlEndocrine Pathology">{{cite web |url=http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html |title=Endocrine Pathology |format= |work= |accessdate=2009-05-08}}</ref>  
* [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types depicted in the flowchart.
* [[Histopathological]]ly, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and [[colloid]] into the following types depicted in the flowchart.
{{Familytree/start}}
{{Familytree/start}}
{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= Thyroid adenoma}}
{{Familytree|boxstyle=background: #E0FFFF;| | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | |A01= Thyroid adenoma}}
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* Microfollicular adenoma (Fetal)
* Microfollicular adenoma (Fetal)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Consist of small, closely packed follicles
* Consist of small, closely packed [[follicles]]
* Have the potential for microinvasion
* Have the potential for [[microinvasion]]
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
Line 34: Line 34:
* Macrofollicular adenoma (colloid adenoma)
* Macrofollicular adenoma (colloid adenoma)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Consists of large amount of colloid
* Consists of large amount of [[colloid]]
* Do not have the potential for microinvasion
* Do not have the potential for [[microinvasion]]
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
Line 42: Line 42:
* Hürthle cell adenoma (oxyphil or oncocytic tumor)
* Hürthle cell adenoma (oxyphil or oncocytic tumor)
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Consists of oxyphil cells
* Consists of [[oxyphil]] cells
* Have the potential for microinvasion
* Have the potential for [[microinvasion]]
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
4
4
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Atypical embryonal adenoma
* Atypical embryonal adenoma
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Consists of embryonic cells
* Consists of embryonic cells
* Have the potential for microinvasion
* Have the potential for [[microinvasion]]
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
Line 60: Line 58:
* Hyalinizing trabecular adenoma
* Hyalinizing trabecular adenoma
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
* Consists of hyalinization
* Consists of [[hyalinization]]
* Have the potential for microinvasion
* Have the potential for [[microinvasion]]
|}
|}
==Reference==
==Reference==
{{Reflist}}
{{Reflist}}

Revision as of 05:06, 12 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Classification

  • Thyroid adenomas are classified into 2 subtype: follicular adenoma and others.
  • Almost all thyroid adenomas are follicular adenomas.[1] Others include papillary adenoma which is very rare.[2]
  • Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.[3]
  • Histopathologically, follicular adenomas can be classified according to their cellular architecture and relative amounts of cellularity and colloid into the following types depicted in the flowchart.
 
 
 
 
 
 
 
 
 
 
 
 
Thyroid adenoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Microfollicular adenoma (fetal adenoma)
 
Macrofollicular adenoma (colloid adenoma)
 
Hürthle cell adenoma (oxyphil or oncocytic tumor)
 
 
 
 
 
Atypical embryonal adenoma
 
Hyalinizing trabecular adenoma
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  • Below is a table with the description of different types of follicular adenoma:[4]
Number Type of follicular adenoma Description

1

  • Microfollicular adenoma (Fetal)

2

  • Macrofollicular adenoma (colloid adenoma)

3

  • Hürthle cell adenoma (oxyphil or oncocytic tumor)

4

  • Atypical embryonal adenoma

5

  • Hyalinizing trabecular adenoma

Reference

  1. ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. p. 1117. ISBN 0-7216-0187-1.
  2. ↑ emedicine > Thyroid, Evaluation of Solitary Thyroid Nodule > Benign Thyroid Nodules By Daniel J Kelley and Arlen D Meyers. Updated: Oct 17, 2008
  3. ↑ "Endocrine Pathology". Retrieved 2009-05-08.
  4. ↑ "TB Classification".
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