Oligodendroglioma other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Other diagnostic studies for oligodendroglioma include biopsy and fish. | Other diagnostic studies for oligodendroglioma include [[biopsy]] and [[fish|Fluorescent in-situ hybridization (FISH) technique]]. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Biopsy=== | ===Biopsy=== | ||
[[Biopsy]] demonstrates | [[Biopsy]] demonstrates | ||
Line 22: | Line 19: | ||
*Biopsy may be performed to help confirm the diagnosis of oligodendroglioma. | *Biopsy may be performed to help confirm the diagnosis of oligodendroglioma. | ||
===Fluorescent in-situ hybridization (FISH) technique=== | |||
*[[FISH]] demonstrates deletions of [[chromosome 1|chromosome 1p]] and [[chromosome 19|19q]].<ref name=turk>{{Citation |last=Tihan |first=Tarik|last=Ersen|first=Ayca |year=2008 |title=Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007 |publisher=Turkish Journal of Pathology |publication-place= |page= |url=http://www.turkjpath.org/text.php3?id=645 |accessdate=9 October, 2015 }}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 16:05, 12 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for oligodendroglioma include biopsy and Fluorescent in-situ hybridization (FISH) technique.
Other Diagnostic Studies
Biopsy
Biopsy demonstrates
- Biopsy may be of two types: open or stereotactic.
- Indications of stereotactic biopsy include:[1]
- Deep-seated tumor that is not amenable to resection
- Lesions in which the radiological and clinical findings are ambiguous
- Diffuse lesions; multiple lesions; an appearance that suggests a lymphoma, which would not require resection
- Change in the appearance of a previously diagnosed or treated tumor
- Assessment of tumor after treatment ( to distinguish between radiation necrosis and tumor recurrence)
- Biopsy may be done at the time of surgical resection of oligodendroglioma.
- Biopsy may be performed to help confirm the diagnosis of oligodendroglioma.
Fluorescent in-situ hybridization (FISH) technique
- FISH demonstrates deletions of chromosome 1p and 19q.[2]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Ersen, Ayca (2008), Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007, Turkish Journal of Pathology, retrieved 9 October, 2015 Check date values in:
|accessdate=
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