Oligodendroglioma other diagnostic studies: Difference between revisions
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===Biopsy=== | ===Biopsy=== | ||
[[Biopsy]] demonstrates | [[Biopsy]] demonstrates | ||
*Biopsy may be done at the time of [[surgical resection]] of oligodendroglioma. | |||
*Biopsy may be performed to help confirm the diagnosis of oligodendroglioma. | |||
*Biopsy may be of two types: [[craniotomy|open]] or [[stereotactic]]. | *Biopsy may be of two types: [[craniotomy|open]] or [[stereotactic]]. | ||
*Indications for [[craniotomy|open biopsy]] and [[stereotactic|stereotactic biopsy]] are described below:<ref name="pmid15509821">{{cite journal| author=Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN| title=Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion. | journal=N Engl J Med | year= 2004 | volume= 351 | issue= 18 | pages= 1875-82 | pmid=15509821 | doi=10.1056/NEJMcpc049025 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15509821 }} </ref> | *Indications for [[craniotomy|open biopsy]] and [[stereotactic|stereotactic biopsy]] are described below:<ref name="pmid15509821">{{cite journal| author=Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN| title=Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion. | journal=N Engl J Med | year= 2004 | volume= 351 | issue= 18 | pages= 1875-82 | pmid=15509821 | doi=10.1056/NEJMcpc049025 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15509821 }} </ref> | ||
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[[craniotomy|Open biopsy]] | [[craniotomy|Open biopsy]] | ||
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*Surgically resectable masses | |||
*Lesions in accessible and relatively “silent” areas of the brain or in areas of the brain with a mild postoperative neurologic deficit | |||
*Appearance consistent with [[tumor]] on the [[MRI]] | |||
*Large tumors exerting mass effect | |||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
[[Stereotactic|Stereotactic biopsy]] | [[Stereotactic|Stereotactic biopsy]] | ||
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*Deep-seated [[tumor]] that is not amenable to resection | |||
*Lesions in which the radiological and clinical findings are ambiguous | |||
*Diffuse lesions; multiple lesions; an appearance that suggests a lymphoma, which would not require resection | |||
*Change in the appearance of a previously diagnosed or treated tumor | |||
*Assessment of tumor after treatment ( to distinguish between [[radiation|radiation necrosis]] and tumor recurrence) | |||
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Revision as of 16:26, 12 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for oligodendroglioma include biopsy and fluorescent in-situ hybridization (FISH) technique.
Other Diagnostic Studies
Biopsy
Biopsy demonstrates
- Biopsy may be done at the time of surgical resection of oligodendroglioma.
- Biopsy may be performed to help confirm the diagnosis of oligodendroglioma.
- Biopsy may be of two types: open or stereotactic.
- Indications for open biopsy and stereotactic biopsy are described below:[1]
| Type of biopsy | Indications |
|---|---|
|
Fluorescent in-situ hybridization (FISH) technique
- FISH demonstrates deletions of chromosome 1p and 19q.[2]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Ersen, Ayca (2008), Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007, Turkish Journal of Pathology, retrieved 9 October, 2015 Check date values in:
|accessdate=(help)