Oligodendroglioma other imaging findings: Difference between revisions
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===Magnetic Resonance Spectroscopy=== | ===Magnetic Resonance Spectroscopy=== | ||
* [[N-acetyl aspartate]] (NAA) peak is dominant | *[[N-acetyl aspartate]] (NAA) peak is dominant | ||
*[[Choline]]-to-[[creatine]] ratio of less than 3:1 | *[[Choline]]-to-[[creatine]] ratio of less than 3:1 | ||
*Reduction of [[N-acetyl aspartate|NAA]]/[[creatine]] ratio | *Reduction of [[N-acetyl aspartate|NAA]]/[[creatine]] ratio | ||
===Magnetic Resonance Perfusion=== | |||
*There is increased "''chicken wire''" network of vascularity, which results in elevated relative cerebral blood volume (rCBV).<ref name=Radio>Radiographic features of oligodendroglioma. Dr. Henry Knipe and Dr. Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma</ref> | |||
*MR perfusion has a sensitivity of 95% for distinguishing grade II from grade III oligodendrogliomas. rCBV above the threshold of 1.75 demonstrates more rapid tumor progression. | |||
===Positron Emission Tomography=== | |||
*[[PET|11C-Methionine PET]] studies can be used to differentiate oligodendroglioma from anaplastic oligodendroglioma. [[Florbetapir (18F)|[18F]-fluorodeoxyglucose]] (FDG) uptake of oligodendroglioma is similar to normal [[white matter]], whereas FDG uptake of [[anaplastic|anaplastic oligodendroglioma]] is similar to normal [[gray matter]].<ref name=Radio>Radiographic features of oligodendroglioma. Dr. Henry Knipe and Dr. Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma</ref> | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other Imaging Findings
Other imaging studies for oligodendroglioma include:[1][2]
Magnetic Resonance Spectroscopy
- N-acetyl aspartate (NAA) peak is dominant
- Choline-to-creatine ratio of less than 3:1
- Reduction of NAA/creatine ratio
Magnetic Resonance Perfusion
- There is increased "chicken wire" network of vascularity, which results in elevated relative cerebral blood volume (rCBV).[3]
- MR perfusion has a sensitivity of 95% for distinguishing grade II from grade III oligodendrogliomas. rCBV above the threshold of 1.75 demonstrates more rapid tumor progression.
Positron Emission Tomography
- 11C-Methionine PET studies can be used to differentiate oligodendroglioma from anaplastic oligodendroglioma. [18F]-fluorodeoxyglucose (FDG) uptake of oligodendroglioma is similar to normal white matter, whereas FDG uptake of anaplastic oligodendroglioma is similar to normal gray matter.[3]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Nikaido K, Nihira H, Wakai S, Honmo O, Tsuzuki A (2003). "[A case of oligodendroglioma with temporal lobe epilepsy initially suspected as having paroxymal tachycardia]". No To Hattatsu. 35 (5): 401–5. PMID 13677949.
- ↑ 3.0 3.1 Radiographic features of oligodendroglioma. Dr. Henry Knipe and Dr. Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma