Gestational trophoblastic neoplasia laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
'''Blood tests''' that may be done include: | '''Blood tests''' that may be done include: | ||
=== | ===Quantitative serum HCG=== | ||
* Human chorionic gonadotropin (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | * [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD. | ||
* HCG is a hormone that the placenta normally produces during pregnancy. | * HCG is a hormone that the placenta normally produces during pregnancy. | ||
* HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine. | * HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine. | ||
* HCG levels are much higher in women with complete hydatidiform | * HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy. | ||
* With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD. | * With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD. | ||
* With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour. | * With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour. | ||
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===Complete blood count=== | ===Complete blood count=== | ||
* [[Complete blood count]] can check for anemia from long-term (chronic) vaginal bleeding. | * [[Complete blood count]] can check for anemia from long-term (chronic) vaginal bleeding. | ||
===Karyotyping=== | ===Karyotyping=== | ||
===Flow cytometry=== | ===Flow cytometry=== | ||
===Immunohistochemistry=== | ===Immunohistochemistry=== | ||
===Kidney function tests=== | |||
===Liver function tests=== | |||
==References== | ==References== |
Revision as of 15:22, 13 October 2015
Overview
Increased quantitative beta HCG levels.
Laboratory Findings
Blood tests that may be done include:
Quantitative serum HCG
- Human chorionic gonadotropin (HCG or b-HCG) is the most common tumour marker test used to diagnose GTD.
- HCG is a hormone that the placenta normally produces during pregnancy.
- HCG is a very sensitive test for diagnosing most gestational trophoblastic tumours. HCG is usually measured in the blood, but it can also be measured in the urine.
- HCG levels are much higher in women with complete hydatidiform moles and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy.
- With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD.
- With placental site tumours, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumour.
- An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward.
Human placental lactogen (hPL)
- Human placental lactogen (hPL) is a tumour marker that may be used to follow women with placental site trophoblastic tumours. High hPL levels are found in women with some types of GTD.
Complete blood count
- Complete blood count can check for anemia from long-term (chronic) vaginal bleeding.