Oligodendroglioma other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Biopsy=== | ===Biopsy=== | ||
On [[biopsy]], oligodendroglioma is characterized by homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus, giving them a “''fried egg''” appearance. | *On [[biopsy]], oligodendroglioma is characterized by homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus, giving them a “''fried egg''” appearance. | ||
*Biopsy may be done at the time of [[surgical resection]] of oligodendroglioma. | *Biopsy may be done at the time of [[surgical resection]] of oligodendroglioma. | ||
*Biopsy may be performed to help confirm the diagnosis of oligodendroglioma. | *Biopsy may be performed to help confirm the diagnosis of oligodendroglioma. | ||
Revision as of 19:03, 13 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for oligodendroglioma include biopsy and fluorescent in-situ hybridization (FISH) technique.
Other Diagnostic Studies
Biopsy
- On biopsy, oligodendroglioma is characterized by homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus, giving them a “fried egg” appearance.
- Biopsy may be done at the time of surgical resection of oligodendroglioma.
- Biopsy may be performed to help confirm the diagnosis of oligodendroglioma.
- Biopsy may be of two types: open and stereotactic.
- Indications for open biopsy and stereotactic biopsy are described below:[1]
| Type of biopsy | Indications |
|---|---|
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Fluorescent in-situ hybridization (FISH) technique
- FISH demonstrates deletions of chromosome 1p and 19q.[2]
References
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Ersen, Ayca (2008), Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007, Turkish Journal of Pathology, retrieved 9 October, 2015 Check date values in:
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