Oligodendroglioma other diagnostic studies: Difference between revisions
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*Deep-seated [[tumor]] that is not amenable to resection | *Deep-seated [[tumor]] that is not amenable to resection | ||
*Lesions in which the radiological and clinical findings are ambiguous | *Lesions in which the radiological and clinical findings are ambiguous | ||
*Diffuse | *Diffuse or multiple lesions | ||
*Appearance that suggests a [[lymphoma]], which would not require resection | |||
*Change in the appearance of a previously diagnosed or treated [[tumor]] | *Change in the appearance of a previously diagnosed or treated [[tumor]] | ||
*Assessment of tumor after treatment (to distinguish between [[radiation|radiation necrosis]] and tumor recurrence) | *Assessment of tumor after treatment (to distinguish between [[radiation|radiation necrosis]] and tumor recurrence) | ||
Revision as of 19:15, 13 October 2015
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Oligodendroglioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Oligodendroglioma other diagnostic studies On the Web |
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American Roentgen Ray Society Images of Oligodendroglioma other diagnostic studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other diagnostic studies for oligodendroglioma include biopsy and fluorescent in-situ hybridization (FISH) technique.
Other Diagnostic Studies
Biopsy
- On biopsy, oligodendroglioma is characterized by homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus and perinuclear halo, giving it the characteristic “fried egg” appearance.[1]
- Biopsy may be done at the time of surgical resection of oligodendroglioma.
- Biopsy may be performed to help confirm the diagnosis of oligodendroglioma.
- Biopsy may be of two types: open and stereotactic.
- Indications for open biopsy and stereotactic biopsy are described below:[2]
| Type of biopsy | Indications |
|---|---|
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Fluorescent in-situ hybridization (FISH) technique
- FISH demonstrates deletions of chromosome 1p and 19q.[3]
References
- ↑ Wesseling P, van den Bent M, Perry A (2015). "Oligodendroglioma: pathology, molecular mechanisms and markers". Acta Neuropathol. 129 (6): 809–27. doi:10.1007/s00401-015-1424-1. PMC 4436696. PMID 25943885.
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Ersen, Ayca (2008), Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007, Turkish Journal of Pathology, retrieved 9 October, 2015 Check date values in:
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