Anaplastic large cell lymphoma laboratory findings: Difference between revisions
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*[[Anemia]] | *[[Anemia]] | ||
*[[Thrombocytopenia]] | *[[Thrombocytopenia]] | ||
*Increased [[LDH]] | *Increased [[LDH]] | ||
* In situ hybridization<ref> Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015</ref> | |||
:* Negative for the Epstein-Barr virus ([[EBV]]) | |||
* Immunohistochemistry: | |||
:* Negative for human herpes virus-8 ([[HHV8]]) | |||
* Immunophenotyping<ref>Dovepress. Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature | * Immunophenotyping<ref>Dovepress. Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature | ||
. https://www.dovepress.com/anaplastic-lymphoma-kinase-positive-anaplastic-large-cell-lymphoma-wit-peer-reviewed-article-OTT Accessed on October 13, 2015</ref> | . https://www.dovepress.com/anaplastic-lymphoma-kinase-positive-anaplastic-large-cell-lymphoma-wit-peer-reviewed-article-OTT Accessed on October 13, 2015</ref> | ||
:* Strongly immunoreactive for [[CD30]], ALK, EMA, and [[vimentin]] | :* Strongly immunoreactive for [[CD30]], ALK, EMA, and [[vimentin]] | ||
:* Negative for AE1/AE3, CK20, CK7, CK5/6, P63, [[SMA]], [[HMB-45]], pan-Melan, S-100, Myo D1, [[synaptophysin]], [[CD56]], [[desmin]], [[CD15]], [[CD20]], | :* Negative for AE1/AE3, CK20, CK7, CK5/6, P63, [[SMA]], [[HMB-45]], pan-Melan, S-100, Myo D1, [[synaptophysin]], [[CD56]], [[desmin]], [[CD15]], [[CD20]], Pax-5, and [[CD3]] | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 20:16, 13 October 2015
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Laboratory Findings[1]
- Anemia
- Thrombocytopenia
- Increased LDH
- In situ hybridization[2]
- Negative for the Epstein-Barr virus (EBV)
- Immunohistochemistry:
- Negative for human herpes virus-8 (HHV8)
- Immunophenotyping[3]
References
- ↑ "ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project".
- ↑ Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma. Hindawi Publishing Corporation. http://www.hindawi.com/journals/ah/2012/529572/#B1 Accessed on October 13, 2015
- ↑ Dovepress. Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature . https://www.dovepress.com/anaplastic-lymphoma-kinase-positive-anaplastic-large-cell-lymphoma-wit-peer-reviewed-article-OTT Accessed on October 13, 2015