Ewing's sarcoma overview: Difference between revisions
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==Classification== | ==Classification== | ||
There is no classification system established for Ewing sarcoma. | There is no classification system established for Ewing sarcoma. | ||
==Pathophysiology== | |||
Ewing sarcoma may occur anywhere in the body, but most commonly in the [[pelvis]] and proximal long tubular bones. The pathogenesis of Ewing sarcoma include t(11;22) chromosomal translocation. On microscopic histopathological analysis, presence of small round cells that have a high nuclear to cytoplasmic ratio, vacuolated cytoplasm, and faded boundaries are characteristic findings of Ewing sarcoma. | |||
==References== | ==References== | ||
Revision as of 20:43, 13 October 2015
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Ewing's sarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Ewing's sarcoma overview On the Web |
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American Roentgen Ray Society Images of Ewing's sarcoma overview |
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Risk calculators and risk factors for Ewing's sarcoma overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-In-Chief: Michael Maddaleni, B.S.
Overview
Ewing's sarcoma is the common name for primitive neuroectodermal tumor. It is a rare disease, and until recently, it had a very low long term survival rate. It is a small round-cell tumor in which cancer cells are found in the bone or in soft tissue (rarer). The most common areas in which it occurs are the pelvis, the femur, the humerus, and the ribs.
Classification
There is no classification system established for Ewing sarcoma.
Pathophysiology
Ewing sarcoma may occur anywhere in the body, but most commonly in the pelvis and proximal long tubular bones. The pathogenesis of Ewing sarcoma include t(11;22) chromosomal translocation. On microscopic histopathological analysis, presence of small round cells that have a high nuclear to cytoplasmic ratio, vacuolated cytoplasm, and faded boundaries are characteristic findings of Ewing sarcoma.