Gestational trophoblastic neoplasia laboratory findings: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
Line 3: | Line 3: | ||
{{CMG}}{{AE}}{{MD}} | {{CMG}}{{AE}}{{MD}} | ||
==Overview== | ==Overview== | ||
Elevated serum [[Human chorionic gonadotropin]] is diagnostic of choriocarcinoma.<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
'''Blood tests''' that may be done include:<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | '''Blood tests''' that may be done include:<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | ||
===Quantitative serum HCG=== | ===Quantitative serum HCG=== | ||
* [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common | * [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common [[tumor]] marker test used to diagnose GTD | ||
* HCG is a very sensitive test for diagnosing most gestational trophoblastic | * HCG is a very sensitive test for diagnosing most gestational trophoblastic tumors. HCG is usually measured in the blood, but it can also be measured in the [[urine]] | ||
* HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy | * HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal [[pregnancy]] | ||
* With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD | * With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD | ||
* With placental site | * With placental site tumors, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumor | ||
* An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward | * An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward | ||
===Human placental lactogen (hPL)=== | ===Human placental lactogen (hPL)=== | ||
* Human placental lactogen (hPL) is a | * Human placental lactogen (hPL) is a tumor marker that may be used to follow women with placental site [[trophoblastic]] tumors. High hPL levels are found in women with some types of GTD. | ||
===Complete blood count=== | ===Complete blood count=== | ||
* [[Complete blood count]] can check for anemia from long-term (chronic) vaginal bleeding. | * [[Complete blood count]] can check for [[anemia ]]from long-term (chronic) [[vaginal bleeding]]. | ||
===Kidney function tests=== | ===Kidney function tests=== | ||
===Liver function tests=== | ===Liver function tests=== | ||
==References== | ==References== | ||
{{reflist|1}} | {{reflist|1}} |
Revision as of 18:44, 15 October 2015
Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
Elevated serum Human chorionic gonadotropin is diagnostic of choriocarcinoma.[1]
Laboratory Findings
Blood tests that may be done include:[1]
Quantitative serum HCG
- Human chorionic gonadotropin (HCG or b-HCG) is the most common tumor marker test used to diagnose GTD
- HCG is a very sensitive test for diagnosing most gestational trophoblastic tumors. HCG is usually measured in the blood, but it can also be measured in the urine
- HCG levels are much higher in women with complete hydatidiform moles and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy
- With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD
- With placental site tumors, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumor
- An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward
Human placental lactogen (hPL)
- Human placental lactogen (hPL) is a tumor marker that may be used to follow women with placental site trophoblastic tumors. High hPL levels are found in women with some types of GTD.
Complete blood count
- Complete blood count can check for anemia from long-term (chronic) vaginal bleeding.
Kidney function tests
Liver function tests
References
- ↑ 1.0 1.1 Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015