Gestational trophoblastic neoplasia laboratory findings: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
Line 6: | Line 6: | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
===Quantitative serum HCG=== | ===Quantitative serum HCG=== | ||
* [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common [[tumor]] marker test used to diagnose GTD<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | * [[Human chorionic gonadotropin]] (HCG or b-HCG) is the most common [[tumor]] marker test used to diagnose GTD<ref name=abc> Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015</ref> | ||
* HCG is markedly elevated (usu. >10,000 IU) | |||
* HCG is a very sensitive test for diagnosing most gestational trophoblastic tumors. HCG is usually measured in the blood, but it can also be measured in the [[urine]] | * HCG is a very sensitive test for diagnosing most gestational trophoblastic tumors. HCG is usually measured in the blood, but it can also be measured in the [[urine]] | ||
* HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal [[pregnancy]] | * HCG levels are much higher in women with complete [[hydatidiform mole]]s and gestational choriocarcinoma compared to HCG levels in women with a normal [[pregnancy]] |
Revision as of 19:12, 15 October 2015
Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
Elevated serum human chorionic gonadotropin is diagnostic of choriocarcinoma.[1]
Laboratory Findings
Quantitative serum HCG
- Human chorionic gonadotropin (HCG or b-HCG) is the most common tumor marker test used to diagnose GTD[1]
- HCG is markedly elevated (usu. >10,000 IU)
- HCG is a very sensitive test for diagnosing most gestational trophoblastic tumors. HCG is usually measured in the blood, but it can also be measured in the urine
- HCG levels are much higher in women with complete hydatidiform moles and gestational choriocarcinoma compared to HCG levels in women with a normal pregnancy
- With partial moles, the HCG level is higher than normal, but it is not as high as with other types of GTD
- With placental site tumors, the HCG level may be slightly higher than normal, but it is not considered a good marker for this type of tumor
- An HCG test can help find GTD after pregnancy or miscarriage as this hormone should not be present in the blood or urine soon afterward
Human placental lactogen (hPL)
- Human placental lactogen (hPL) is a tumor marker that may be used to follow women with placental site trophoblastic tumors. High hPL levels are found in women with some types of GTD.
Complete blood count
- Complete blood count can check for anemia from long-term (chronic) vaginal bleeding.
Kidney function tests
Liver function tests
References
- ↑ 1.0 1.1 Diagnosing gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/diagnosis/?region=ns Accessed on October 13, 2015