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[[File:Axial MRI scan.jpg|thumb|none|200px|Axial MRI showing retinoblastoma<ref name="radio1">Image courtesy of Radswiki [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-3]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
[[File:Axial MRI scan.jpg|thumb|none|200px|Axial MRI showing retinoblastoma<ref name="radio1">Image courtesy of Radswiki [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-3]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
[[File:T1 MRI of retinoblastoma.jpg|thumb|none|200px|T1 MRI showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Vinay Shah [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-9]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
[[File:T1 MRI of retinoblastoma.jpg|thumb|none|200px|T1 MRI showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Vinay Shah [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-9]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
[[
[[File:T2 MRI of retinoblastoma.jpg|thumb|none|200px|T2 MRI showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Vinay Shah [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-9]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]
 
File:T2 MRI of retinoblastoma.jpg|thumb|none|200px|T2 MRI showing retinoblastoma<ref name="radio1">Image courtesy of Dr. Vinay Shah [http://www.radiopaedia.org Radiopaedia] (original file [http://radiopaedia.org/cases/retinoblastoma-9]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC</ref>]]


==References==
==References==

Revision as of 13:36, 16 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [3]

Overview

On head and neck MRI, retinoblastoma is characterized by isointense to hypointense mass on T1-weighted MRI, and hyperintense mass on T2-weighted MRI.[1]

MRI

MRI is the modality of choice for pre-treatment staging on retinoblastoma.

  • The MRI features of retinoblastoma include:[1]
MRI component Features
T1
  • intermediate signal intensity, hyperintense c.f. vitreous
T2
  • hypointense c.f. vitreous
T1 C+ (Gd)
  • The mass usually enhances relatively homogeneously when small
  • Larger tumours often have areas of necrosis, rendering it heterogeneous
  • Linear enhancement of the choroid beyond the margins of the tumour should raise the possibility of choroidal involvement, although inflammation may lead to similar appearance
  • Enhancement of the anterior chamber need not represent tumour involvement, with hyperaemia, uveitis and iris neovascularisation all leading to asymmetric enhancement
  • Careful assessment of the optic disc and optic nerve should be carried out to assess for involvement
  • Extra-ocular extension through the sclera will be visible as interruption of the otherwise hypointense non-enhancing sclera by enhancing tumour
DWI
  • The tumour shows restricted diffusion on DWI at high b values. It exhibits low ADC values in contrast to the high intensity of the vitreous in the ADC maps
  • ADC map can be used to differentiate viable and necrotic tumour
  • DWI is valuable in evaluating the response to eye-preservation treatment
Axial MRI showing retinoblastoma[2]
T1 MRI showing retinoblastoma[2]
T2 MRI showing retinoblastoma[2]

References

  1. ↑ 1.0 1.1 Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10 2015
  2. ↑ 2.0 2.1 2.2 Image courtesy of Radswiki Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC

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