Renal oncocytoma pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma. | |||
==Pathogenesis== | ==Pathogenesis== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma.
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter).
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli with excessive amounts of mitochondria.