Renal oncocytoma pathophysiology: Difference between revisions
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{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma. | On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the [[tumor]] of renal oncocytoma. | ||
==Pathogenesis== | ==Pathogenesis== | ||
* Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney. | * Renal oncocytoma is thought to arise from the [[intercalated cells]] of [[collecting ducts]] of the [[kidney]]. | ||
==Gross Pathology== | ==Gross Pathology== | ||
* The tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter). | * The [[tumors]] are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter). | ||
==Microscopic Pathology== | ==Microscopic Pathology== | ||
* An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli with excessive amounts of mitochondria. | * An epithelial tumor composed of [[oncocytes]], large [[eosinophilic]] cells having small, round, benign-appearing [[nuclei]] with large [[nucleoli]] with excessive amounts of [[mitochondria]]. | ||
==References== | ==References== |
Revision as of 12:35, 28 October 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
On gross pathology, tan or mahogany brown, well circumscribed, and central scar are characteristic findings of the tumor of renal oncocytoma.
Pathogenesis
- Renal oncocytoma is thought to arise from the intercalated cells of collecting ducts of the kidney.
Gross Pathology
- The tumors are tan or mahogany brown, well circumscribed and contain a central scar. They may achieve a large size (up to 12 cm in diameter).
Microscopic Pathology
- An epithelial tumor composed of oncocytes, large eosinophilic cells having small, round, benign-appearing nuclei with large nucleoli with excessive amounts of mitochondria.