Cystic nephroma: Difference between revisions
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{{Cystic nephroma}} | {{Cystic nephroma}} | ||
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''. | |||
{{CMG}} | {{CMG}} | ||
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==[[Cystic nephroma overview|Overview]]== | |||
==[[Cystic nephroma historical perspective|Historical Perspective]]== | |||
==[[Cystic nephroma classification|Classification]]== | |||
==[[Cystic nephroma pathophysiology|Pathophysiology]]== | |||
==[[Cystic nephroma causes|Causes]]== | |||
==[[Cystic nephroma differential diagnosis|Differentiating Cystic nephroma]]== | |||
==[[Cystic nephroma epidemiology and demographics|Epidemiology and Demographics]]== | |||
==[[Cystic nephroma risk factors|Risk Factors]]== | |||
==[[Cystic nephroma screening|Screening]]== | |||
==[[Cystic nephroma natural history|Natural History, Complications and Prognosis]]== | |||
==Diagnosis== | |||
[[Cystic nephroma staging|Staging]] | [[Cystic nephroma history and symptoms|History and Symptoms]] | [[Cystic nephroma physical examination|Physical Examination]] | [[Cystic nephroma laboratory findings|Laboratory Findings]] | [[Cystic nephroma x ray|X Ray]] | [[Cystic nephroma CT|CT]] | [[Cystic nephroma MRI|MRI]] [[Cystic nephroma ultrasound|Ultrasound]] | [[Cystic nephroma other imaging findings|Other Imaging Findings]] | [[Cystic nephroma other diagnostic studies|Other Diagnostic Studies]] | [[Cystic nephroma biopsy|Biopsy]] | |||
==Treatment== | |||
[[Cystic nephroma medical therapy|Medical therapy]] | [[Cystic nephroma surgery|Surgery]] | [[Cystic nephroma primary prevention|Primary prevention]] | [[Cystic nephroma secondary prevention|Secondary prevention]] | [[Cystic nephroma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Cystic nephroma future or investigational therapies|Future or Investigational Therapies]] | |||
==Overview== | ==Overview== | ||
A '''cystic nephroma''', also known as '''multilocular cystic nephroma''', '''mixed epithelial stromal tumour (MEST)''' and '''renal epithelial stromal tumour (REST)''',<ref name=pmid17414095>{{cite journal |vauthors=Turbiner J, Amin MB, Humphrey PA, etal |title=Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term |journal=Am. J. Surg. Pathol. |volume=31 |issue=4 |pages=489–500 |date=April 2007 |pmid=17414095 |doi=10.1097/PAS.0b013e31802bdd56 |url=}}</ref> is a type of rare [[benign tumor|benign]] [[kidney tumour]]. | A '''cystic nephroma''', also known as '''multilocular cystic nephroma''', '''mixed epithelial stromal tumour (MEST)''' and '''renal epithelial stromal tumour (REST)''',<ref name=pmid17414095>{{cite journal |vauthors=Turbiner J, Amin MB, Humphrey PA, etal |title=Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term |journal=Am. J. Surg. Pathol. |volume=31 |issue=4 |pages=489–500 |date=April 2007 |pmid=17414095 |doi=10.1097/PAS.0b013e31802bdd56 |url=}}</ref> is a type of rare [[benign tumor|benign]] [[kidney tumour]]. | ||
Revision as of 17:29, 29 October 2015
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American Roentgen Ray Society Images of Cystic nephroma |
For patient information click here.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords:
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Cystic nephroma
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging | History and Symptoms | Physical Examination | Laboratory Findings | X Ray | CT | MRI Ultrasound | Other Imaging Findings | Other Diagnostic Studies | Biopsy
Treatment
Medical therapy | Surgery | Primary prevention | Secondary prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Overview
A cystic nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour (MEST) and renal epithelial stromal tumour (REST),[1] is a type of rare benign kidney tumour.
Symptoms
Cystic nephromas are often asymptomatic. They are typically discovered on medical imaging incidentally (i.e. an incidentaloma).
Diagnosis
Cystic nephromas are diagnosed by biopsy or excision. It is important to correctly diagnose them as, radiologically, they may mimic the appearance of a renal cell carcinoma that is cystic.[2]
Pathologic diagnosis
The characteristics of cystic nephromas are:
- Cysts lined by a simple epithelium with a hobnail morphology, i.e. the nuclei of the cyst lining epithelium bulges into the lumen of the cysts,
- Ovarian-like stroma that has a:
- Spindle cell morphology, and has a
- Basophilic cytoplasm.
Cystic nephromas have an immunostaining pattern like ovarian stroma; they are positive for:
Differential diagnosis
- cystic partially differentiated nephroblastoma
- cystic standard nephroblastoma (cystic Wilm's tumor)
- cystic mesoblastic nephroma
- cystic renal cell carcinoma
- other renal cysts
References
- ↑ Turbiner J, Amin MB, Humphrey PA, et al. (April 2007). "Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term". Am. J. Surg. Pathol. 31 (4): 489–500. doi:10.1097/PAS.0b013e31802bdd56. PMID 17414095.
- ↑ Small JE et al. Cystic Nephroma. BrighamRAD Teaching Case Database. URL: http://brighamrad.harvard.edu/Cases/bwh/hcache/385/full.html. Accessed: July 25, 2009.