Hepatocellular adenoma risk factors: Difference between revisions
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:*[[Norgestimate and Ethinyl estradiol]] | :*[[Norgestimate and Ethinyl estradiol]] | ||
:*[[Norgestrel and Ethinyl estradiol]] | :*[[Norgestrel and Ethinyl estradiol]] | ||
* The risk is proportional to the hormonal dose and duration of medication. | * The risk is proportional to the hormonal dose and duration of medication. | ||
==Risk factors for malignant transformation== | |||
The risk factor for malignant transformation of hepatic adenoma to hepatocellular carcinoma is:<ref name="pmid25786843">{{cite journal| author=Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H| title=[Hepatocellular adenoma - new classification and recommendations]. | journal=Ugeskr Laeger | year= 2015 | volume= 177 | issue= 12 | pages= | pmid=25786843 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25786843 }} </ref> | |||
:* Gender (men) | |||
:* Size (> 8 cm) | |||
:* Subtype of hepatocellular adenoma | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
The most potent risk factor in the development of hepatocellular adenoma is use of oral contraceptive pills.[1]
Hepatocellular adenoma risk factors
The most potent risk factor in the development of hepatocellular adenoma is use of oral contraceptive pills.[1][2]
- The risk is proportional to the hormonal dose and duration of medication.
Risk factors for malignant transformation
The risk factor for malignant transformation of hepatic adenoma to hepatocellular carcinoma is:[3]
- Gender (men)
- Size (> 8 cm)
- Subtype of hepatocellular adenoma
References
- ↑ 1.0 1.1 How do oral contraceptives affect liver cancer risk. National Cancer Institute 2015. http://www.cancer.gov/about-cancer/causes-prevention/risk/hormones/oral-contraceptives-fact-sheet
- ↑ Barthelmes L, Tait IS (2005). "Liver cell adenoma and liver cell adenomatosis". HPB (Oxford). 7 (3): 186–96. doi:10.1080/13651820510028954. PMC 2023950. PMID 18333188.
- ↑ Aamann L, Schultz N, Fallentin E, Hamilton-Dutoit S, Vogel I, Grønbæk H (2015). "[Hepatocellular adenoma - new classification and recommendations]". Ugeskr Laeger. 177 (12). PMID 25786843.