Sandbox:DDx HEENT: Difference between revisions
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* RET proto-oncogene activation | * RET proto-oncogene activation | ||
* BRAF oncogene activation | * BRAF oncogene activation | ||
* NTRK1 | |||
Revision as of 15:51, 1 November 2015
- 30-50 yo Caucasian women
- Ionizing radiation exposure
- Positive family history
- Asymptomatic painless neck nodule
- Elevated thyroglobulin level
- HBME-1 stain +ve
- ATP5E stain +ve
- Orphan Annie eye nuclear inclusions
- Psammoma bodies
- Unencapsulated
- Lymphatic spread
- Multifocal
- Solitary mass with irregular borders and increased vascularity on U/S
- Located at the subcapsular region
- Small punctate regions of echogenicity due to calcification
- Lymph node metastases present
- RET proto-oncogene activation
- BRAF oncogene activation
- NTRK1