Sandbox:DDx HEENT: Difference between revisions
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40-60 yo women | |||
Painless thyroid nodule | |||
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* Solitary mass with irregular borders and increased vascularity on U/S | * Solitary mass with irregular borders and increased vascularity on U/S | ||
* | * Lytic bone lesions or multiple lung masses due to hematogenous spread | ||
* Rare lymph node metastases | |||
* | |||
* RAS oncogene activation | * RAS oncogene activation | ||
* PAX8-PPAR gamma 1 genes rearrangement | * PAX8-PPAR gamma 1 genes rearrangement | ||
Revision as of 16:05, 1 November 2015
40-60 yo women
Painless thyroid nodule
- Elevated thyroglobulin level
- HBME-1 stain +ve and ATP5E stain +ve
- Orphan Annie eye and Psammoma bodies
- Unencapsulated multifocal tumor lesions
- Positive lymphatic spread
- Solitary mass with irregular borders and increased vascularity on U/S
- Lytic bone lesions or multiple lung masses due to hematogenous spread
- Rare lymph node metastases
- RAS oncogene activation
- PAX8-PPAR gamma 1 genes rearrangement