Sandbox:DDx HEENT: Difference between revisions
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* Elevated CEA | * Elevated CEA | ||
* Nested | * Nested cellular pattern separated by delicate vascular septa | ||
* Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits | * Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits | ||
* Vascular stroma with hemorrhage, edema, and coarse calcification | * Vascular stroma with hemorrhage, edema, and coarse calcification | ||
Revision as of 16:59, 1 November 2015
- 35 yo women
- May have diarrhea, flushing, and pruritis
- MEN2 (pheochromocytoma and hyperparathyroidism symptoms)
- Painless thyroid nodule
- Neck lymphadenopathy
- Elevated calcitonin
- Elevated chromogranin
- Elevated CEA
- Nested cellular pattern separated by delicate vascular septa
- Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits
- Vascular stroma with hemorrhage, edema, and coarse calcification
- C-cell hyperplasia may be present
- RET proto-oncogene