Sandbox:DDx HEENT: Difference between revisions

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* Extensive lymphadenopathy  
* Extensive lymphadenopathy  


* Painless thyroid nodule
* BRAF gene mutation
* Neck lymphadenopathy
* p53 gene mutation
 
* Elevated calcitonin
* Elevated chromogranin
* Elevated CEA
 
* Multiple hypoechoegenic lesions on U/s
* Lymph node calcifications
* Liver metastasis
* Nested cellular pattern separated by delicate vascular septa
* Polygonal cells, round nuclie with coarse chromatin, granular cytoplasm, surrounded by amyloid deposits
* Vascular stroma with hemorrhage, edema, and coarse calcification
* C-cell hyperplasia may be present
 
 
* RET proto-oncogene

Revision as of 17:26, 1 November 2015

  • 65 yo women
  • Rapidly enlarging neck mass
  • Neck pain, dyspnea, dysphagia, and hoarseness
  • Constitutional symptoms
  • Tender hard nodular goiter
  • Extensive lymphadenopathy
  • BRAF gene mutation
  • p53 gene mutation
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