Sandbox:DDx HEENT: Difference between revisions

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* 20–40 yo patients
* 40 yo male smoker
* Facial palsy
* May have nasal congestion, obstruction, visual changes, or trismus


* Painless, slow-growing, hard, firm  mass
* Slow growing, painless, well circumscribed
* Located at the parotid gland area
* Located at the angle of the mandible
* Cervical lymphadenopathy
* Ulceration of buccal mucosa




* Low-grade: well-circumscribed cystic masses
* Cystic spaces surrounded by two uniform rows of cells
* High-grade: poorly defined margins, infiltrate locally and appear solid
* Centrally placed pyknotic nuclei
* Calcification may be present
* Papillary infoldings
* Lymphoid stroma and germinal center formation
* No myoepithelial component


* Solid or cystic architecture
* A mixture of epidermoid squamous, intermediate, mucous, and clear cells
* Mucin vacuoles
* Nuclear distortion and cytoplasmic clearing


* t(11;19)(q21;p13)
* Bilaterally cystic lesion
* MECT1-MAML2 fusion gene
* Located posteriorly within the parotidfocal tumour nodulerelatively well defined
* No calcification

Revision as of 12:59, 2 November 2015

  • 40 yo male smoker
  • Slow growing, painless, well circumscribed
  • Located at the angle of the mandible


  • Cystic spaces surrounded by two uniform rows of cells
  • Centrally placed pyknotic nuclei
  • Papillary infoldings
  • Lymphoid stroma and germinal center formation
  • No myoepithelial component


  • Bilaterally cystic lesion
  • Located posteriorly within the parotidfocal tumour nodulerelatively well defined
  • No calcification
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