Sandbox:DDx HEENT: Difference between revisions

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* Bimodal age distribution
* 50 yo women
* Involves minor salivary glands
* well circumscribed painless nodule in the palate or buccal mucosa


* Slowly enlarging mass in the parotid region
* Cystic cavities lined by cuboidal epithelial cells
* Intraluminal projections
* Serous, mucinous, or papillary histology


* Bilateral and multicentric
 
* Nonspecific appearance on CT
* Benign cystic lesion
* Hypoattenuating regions of central necrosis
* Hypodense, small, rounded mass
* Irregular enhancing solid component
* Locate in the mouth floor




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* Uniform serous cells with pleomorphic nuclei and  basophilic granular cytoplasms
* Uniform serous cells with pleomorphic nuclei and  basophilic granular cytoplasms
* Increased mitotic activity and foci of necrosis
* Increased mitotic activity and foci of necrosis
* Lymphoid stroma
* Lymphoid stroma with inflammatory infiltrate


* c-KIT mutation
* c-KIT mutation

Revision as of 14:39, 2 November 2015

  • 50 yo women
  • Involves minor salivary glands
  • well circumscribed painless nodule in the palate or buccal mucosa


  • Cystic cavities lined by cuboidal epithelial cells
  • Intraluminal projections
  • Serous, mucinous, or papillary histology


  • Benign cystic lesion
  • Hypodense, small, rounded mass
* Locate in the mouth floor


  • Tubular, cribriform, and solid growth pattern
  • Uniform serous cells with pleomorphic nuclei and basophilic granular cytoplasms
  • Increased mitotic activity and foci of necrosis
  • Lymphoid stroma with inflammatory infiltrate
  • c-KIT mutation