Sandbox:DDx HEENT: Difference between revisions

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* Develop in the first weeks after birth
Positive history of EBV or HIV infection
* Rapid growth over a period of months
4-7 yo males
* Self involute


* Superficial bright red swelling on the skin
Sheets of a monotonous lymphoid cells, basophilic cytoplasm, four small nucleoli.
* Veins radiate out from the lesion
High proliferative and apoptotic activity
* Deep gray to blue rubbery lumps
scattered tingible body-laden macrophage
"starry sky"appearance




 
t(8;14)(q24;q32)
 
c-myc gene disregulation
* Multiple high-signal-intensity lobules on T2-weighted MRI with flow voids representing vessels of different sizes
* Punctate low-signal-intensity areas indicate calcification or thrombosis
 
 
* Disorganized proliferation of dilated ,thin walled , leaky blood vessels with numerous red blood cells
* Lined by atypical endothelial cells
* Intravascular calcification and thrombosis
 
* VEGF over expression

Revision as of 17:28, 4 November 2015

Positive history of EBV or HIV infection 4-7 yo males

Sheets of a monotonous lymphoid cells, basophilic cytoplasm, four small nucleoli. High proliferative and apoptotic activity scattered tingible body-laden macrophage "starry sky"appearance


t(8;14)(q24;q32) c-myc gene disregulation

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