Ovarian germ cell tumor pathophysiology: Difference between revisions
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* Microscopic examination | * Microscopic examination | ||
* typically reveals uniform cells that resemble primordial germ cells. Typically, thestroma contains lymphocytes and about 20% of patients have sarcoid-like granulomas. | * typically reveals uniform cells that resemble primordial germ cells. Typically, thestroma contains lymphocytes and about 20% of patients have sarcoid-like granulomas. | ||
EST can have a multitude of morphologic patterns including: reticular, endodermal sinus-like, microcystic, papillary, solid, glandular, alveolar, polyvesicular vitelline, enteric and hepatoid. | |||
[[Schiller-Duval bodies]] on [[histology]] are [[pathognomonic]] and seen in the context of the endodermal sinus-like pattern. | |||
Revision as of 18:49, 5 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Dysgerminomas
- On gross examination,
- dysgerminomas present with a smooth, bosselated (knobby) external surface, and is soft, fleshy and either cream-coloured, gray, pink or tan when cut.
- Microscopic examination
- typically reveals uniform cells that resemble primordial germ cells. Typically, thestroma contains lymphocytes and about 20% of patients have sarcoid-like granulomas.
EST can have a multitude of morphologic patterns including: reticular, endodermal sinus-like, microcystic, papillary, solid, glandular, alveolar, polyvesicular vitelline, enteric and hepatoid.
Schiller-Duval bodies on histology are pathognomonic and seen in the context of the endodermal sinus-like pattern.