Waldenström's macroglobulinemia

Waldenström's macroglobulinemia Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Waldenström's macroglobulinemia from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Bone Marrow Aspiration and Biopsy
Electrophoresis and Immunofixation
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Waldenström's macroglobulinemia On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Waldenström's macroglobulinemia All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Waldenström's macroglobulinemia
CDC on Waldenström's macroglobulinemia
Waldenström's macroglobulinemia in the news
Blogs on Waldenström's macroglobulinemia
Directions to Hospitals Treating Waldenström's macroglobulinemia
Risk calculators and risk factors for Waldenström's macroglobulinemia

For patient information on this page, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]

Synonyms and keywords: Primary macroglobulinemia; B-cell lymphoproliferative disease; Lymphoplasmacytoid lymphoma, Lymphoplasmacytoid Lymphomas; Macroglobulinemia; Plasmacytoid lymphocytic lymphoma; Familial Waldenstrom's Macroglobulinaemia; Familial Waldenstrom Macroglobulinaemia

Classification

The World Health Organization placed Waldenström's macroglobulinemia under the category of lymphoplasmacytic lymphomas, which is a subcategory of low-grade Non-Hodgkin lymphoma.

Causes

• The most common causes are a somatic mutation in MYD88 (90% of patients) and a somatic mutation in CXCR4 (27% of patients).

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Bone Marrow Aspiration and Biopsy | Electrophoresis and Immunofixation | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1