Sandbox: DDx Kidney mass: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
Angiomyolipoma
Angiomyolipoma


25-35 yo males
* 25-35 yo males
Asymptomatic
* Asymptomatic
Fever, flank pain ,hematuria, hypertension, nausea, vomiting,
* Fever, flank pain ,hematuria, hypertension, nausea, vomiting,
Tuberous sclerosis
* Tuberous sclerosis


Palpable mass
* Palpable mass
Hypovolemic shock if ruptured  
* Hypovolemic shock if ruptured  


Anemia
* Anemia




Blood vessels, smooth muscle, and mature adipose tissue
* Blood vessels, smooth muscle, and mature adipose tissue
Hemorrhage and necrosis
* Hemorrhage and necrosis






Well circumscribe highly echogenic mass on ultrasonography
* Well circumscribe highly echogenic mass on ultrasonography
Negative Hounsfield units (HU) on CT scan
* Negative Hounsfield units (HU) on CT scan
Calcification is rare  
* Calcification is rare  




TSC1 and TSC2 gene mutation
* TSC1 and TSC2 gene mutation
HMB45 Positive
* HMB45 Positive





Revision as of 20:27, 9 November 2015

Angiomyolipoma

  • 25-35 yo males
  • Asymptomatic
  • Fever, flank pain ,hematuria, hypertension, nausea, vomiting,
  • Tuberous sclerosis
  • Palpable mass
  • Hypovolemic shock if ruptured
  • Anemia


  • Blood vessels, smooth muscle, and mature adipose tissue
  • Hemorrhage and necrosis


  • Well circumscribe highly echogenic mass on ultrasonography
  • Negative Hounsfield units (HU) on CT scan
  • Calcification is rare


  • TSC1 and TSC2 gene mutation
  • HMB45 Positive



Angiosarcoma


Nonmalignant causes

anaplastic sarcoma clear cell sarcoma mesoblastic nephroma metanephric stromal tumor nephroblastomatosis / nephrogenic rests neuroblastoma oncocytoid carcinoma after neuroblastoma ossifying