Essential thrombocytosis history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
People with essential thrombocytosis are usually asymptomatic. Symptoms<ref name="pmid17210076">{{cite journal| author=Brière JB| title=Essential thrombocythemia. | journal=Orphanet J Rare Dis | year= 2007 | volume= 2 | issue= | pages= 3 | pmid=17210076 | doi=10.1186/1750-1172-2-3 | pmc=PMC1781427 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17210076 }} </ref> | People with essential thrombocytosis are usually asymptomatic. Symptoms<ref name="pmid17210076">{{cite journal| author=Brière JB| title=Essential thrombocythemia. | journal=Orphanet J Rare Dis | year= 2007 | volume= 2 | issue= | pages= 3 | pmid=17210076 | doi=10.1186/1750-1172-2-3 | pmc=PMC1781427 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17210076 }} </ref> of essential thrombocytosis include vision disturbances, transient loss of consciousness, chest pain, intense burning pain in hands or feet ([[erythromelalgia]]), numbness and tingling of hands and feet, persistent and painful erection of the penis ([[priapism]]). Neurologic symptoms like headache may occur but the pathophysiology is not completely understood.<ref name="pmid17210076">{{cite journal| author=Brière JB| title=Essential thrombocythemia. | journal=Orphanet J Rare Dis | year= 2007 | volume= 2 | issue= | pages= 3 | pmid=17210076 | doi=10.1186/1750-1172-2-3 | pmc=PMC1781427 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17210076 }} </ref> A positive family history of may be present in those with familial essential thrombocytosis. | ||
==History and symptoms== | ==History and symptoms== | ||
*People with essential thrombocytosis are usually asymptomatic. Patients may have symptoms of minimal bleeding that can go unnoticed until diagnosis. Most of the symptoms are vascular, either from thrombi occluding small and large blood vessels, though any blood vessel may be involved. Symptoms depend on the blood vessel that is involved. | *People with essential thrombocytosis are usually asymptomatic. Patients may have symptoms of minimal bleeding that can go unnoticed until diagnosis. Most of the symptoms are vascular, either from thrombi occluding small and large blood vessels, though any blood vessel may be involved or from bleeding. Symptoms depend on the blood vessel that is involved. | ||
*Symptoms of vascular occlusion: | *Symptoms of vascular occlusion: | ||
**[[Dizziness]] | **[[Dizziness]] | ||
**Vision disturbances (transient monocular blindness, scintillating scotomas, blurred vision)<ref name="pmid9263353">{{cite journal| author=Koudstaal PJ, Koudstaal A| title=Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin. | journal=Semin Thromb Hemost | year= 1997 | volume= 23 | issue= 4 | pages= 365-70 | pmid=9263353 | doi=10.1055/s-2007-996110 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9263353 }} </ref> | **Vision disturbances (transient monocular blindness, scintillating scotomas, blurred vision)<ref name="pmid9263353">{{cite journal| author=Koudstaal PJ, Koudstaal A| title=Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin. | journal=Semin Thromb Hemost | year= 1997 | volume= 23 | issue= 4 | pages= 365-70 | pmid=9263353 | doi=10.1055/s-2007-996110 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9263353 }} </ref> | ||
**Chest pain | **Chest pain | ||
**Intense burning pain in hands or feet(erythromelalgia) | **[[Transient ischemic attack]]s | ||
**Intense burning pain in hands or feet (erythromelalgia) | |||
**Numbness and tingling of hands and feet | **Numbness and tingling of hands and feet | ||
**Persistent and painful penile erections ([[Priapism]]) | **Persistent and painful penile erections ([[Priapism]]) | ||
Revision as of 13:43, 17 November 2015
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Essential thrombocytosis Microchapters |
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Differentiating Essential thrombocytosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
People with essential thrombocytosis are usually asymptomatic. Symptoms[1] of essential thrombocytosis include vision disturbances, transient loss of consciousness, chest pain, intense burning pain in hands or feet (erythromelalgia), numbness and tingling of hands and feet, persistent and painful erection of the penis (priapism). Neurologic symptoms like headache may occur but the pathophysiology is not completely understood.[1] A positive family history of may be present in those with familial essential thrombocytosis.
History and symptoms
- People with essential thrombocytosis are usually asymptomatic. Patients may have symptoms of minimal bleeding that can go unnoticed until diagnosis. Most of the symptoms are vascular, either from thrombi occluding small and large blood vessels, though any blood vessel may be involved or from bleeding. Symptoms depend on the blood vessel that is involved.
- Symptoms of vascular occlusion:
- Dizziness
- Vision disturbances (transient monocular blindness, scintillating scotomas, blurred vision)[2]
- Chest pain
- Transient ischemic attacks
- Intense burning pain in hands or feet (erythromelalgia)
- Numbness and tingling of hands and feet
- Persistent and painful penile erections (Priapism)
- Symptoms from bleeding can occur despite the increased platelet count accounting to the dysfunctional platelets. Common sites of bleeding include eyes, nose (epistaxis), gums, gastrointestinal tract, skin (bruises). The bleeding itself is usually minimal.
- Neurologic symptoms like headache may occur but the pathophysiology is not completely understood.[1]
References
- ↑ 1.0 1.1 1.2 Brière JB (2007). "Essential thrombocythemia". Orphanet J Rare Dis. 2: 3. doi:10.1186/1750-1172-2-3. PMC 1781427. PMID 17210076.
- ↑ Koudstaal PJ, Koudstaal A (1997). "Neurologic and visual symptoms in essential thrombocythemia: efficacy of low-dose aspirin". Semin Thromb Hemost. 23 (4): 365–70. doi:10.1055/s-2007-996110. PMID 9263353.