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{{CMG}}{{AE}} {{MGS}}
{{CMG}}{{AE}} {{MGS}}


{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px"
{| class="wikitable"
|valign=top|
! style="font-weight: bold;" | Treatment regimen
|+
! style="text-align: center; font-weight: bold;" | Drugs
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Treatment regimen  }}
! style="text-align: center; font-weight: bold;" | Side effects
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Side effects}}
|-
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
| CHOP-R regimen
'''CHOP-R regimen'''
| *Cyclophosphamide
| style="padding: 5px 5px; background: #F5F5F5;" |
*Doxorubicin
| Cyclophosphamide
*Vincristine
| Nausea
*Prednisone
|-
*Rituximab
| Doxorubicin
| *Nausea
| Alopecia
*Alopecia
|-
*Granulocytopenia
| Vincristine
| Granulocytopenia
|-
| Prednisone
|
|-
| Rituximab
|  
|-
|
|
|-
|-
| Ibrutinib
| Ibrutinib
| Fatigue
| *Ibrutinib
|-
| *Fatigue
|
*Cytopenia
| Cytopenia
|-
|
|
|-
| Rituximab
| Infusion related reaction
|-
|
| Infections
|-
|
|
|-
| FR regimen:
|
|-
| Fludarabine
| Neutropenia (63%)
|-
| Rituximab
| Thrombocytopenia
|-
|
| Pneumonia
|-
|
|
|-
| BDR regimen:
|
|-
| Bortezomib
| Peripheral Neuropathy - reversible in 61% of patients
|-
| Dexamethasone
|
|-
|-
| Rituximab
| Rituximab
|  
| *Rituximab
|-
| *Infusion related reaction
|
*Infections
|
|-
| DRC regimen:
|
|-
| Dexamethasone
| Neutropenia
|-
| Rituximab
|  
|-
| Cyclophosphamide
|
|-
|
|
|-
|-
| CR regimen:
| FR regimen
|  
| *Fludarabine
*Rituximab
| *Neutropenia (63%)
*Thrombocytopenia
*Pneumonia
|-
|-
| Cladribine
| BDR regimen
| Anemia
| *Bortezomib
*Dexamethasone
*Rituximab
| *Peripheral Neuropathy - reversible in 61% of patients
|-
|-
| Rituximan
| DRC regimen
| Neurological Symptoms
| *Dexamethasone
*Rituximab
*Cyclophosphamide
| *Neutropenia
|-
|-
|  
| CR regimen
| symptomatic cryoglobunemia
| *Cladribine
*Rituximab
| *Anemia
*Neurological symptoms
*Symptomatic cryoglobulinemia
*Thrombocytopenia
|-
|-
|
 
| Thrombocytopenia
 
|}


==References==
==References==

Revision as of 16:53, 17 November 2015

Waldenström's macroglobulinemia Microchapters

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Overview

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Directions to Hospitals Treating Waldenström's macroglobulinemia

Risk calculators and risk factors for Sandbox:MGS

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]

References

Template:WH Template:WS

Treatment regimen Drugs Side effects
CHOP-R regimen *Cyclophosphamide
  • Doxorubicin
  • Vincristine
  • Prednisone
  • Rituximab
 *Nausea
  • Alopecia
  • Granulocytopenia
Ibrutinib *Ibrutinib *Fatigue
  • Cytopenia
Rituximab *Rituximab *Infusion related reaction
  • Infections
FR regimen *Fludarabine
  • Rituximab
 *Neutropenia (63%)
  • Thrombocytopenia
  • Pneumonia
BDR regimen *Bortezomib
  • Dexamethasone
  • Rituximab
 *Peripheral Neuropathy - reversible in 61% of patients
DRC regimen *Dexamethasone
  • Rituximab
  • Cyclophosphamide
 *Neutropenia
CR regimen *Cladribine
  • Rituximab
 *Anemia
  • Neurological symptoms
  • Symptomatic cryoglobulinemia
  • Thrombocytopenia
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