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{{CMG}}{{AE}} {{MGS}}
{{CMG}}{{AE}} {{MGS}}


{| class="wikitable"
{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px"
! style="font-weight: bold;" | Treatment Regimen
|valign=top|
! style="text-align: center; font-weight: bold;" | Drug
|+
! style="text-align: center; font-weight: bold;" | Side effects
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Treatment Regimen}}
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Drugs}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|Side effects}}
|-
|-
| CHOP-R regimen
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''CHOP-R regimen'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Cyclophosphamide
*Cyclophosphamide
*Doxorubicin
*Doxorubicin
Line 15: Line 18:
*Prednisone
*Prednisone
*Rituximab
*Rituximab
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Nausea
*Nausea
*Alopecia
*Alopecia
*Granulocytopenia
*Granulocytopenia
|-
|-
| Ibrutinib
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''Ibrutinib'''
---
| style="padding: 5px 5px; background: #F5F5F5;" |
|  
*Ibrutinib
| style="padding: 5px 5px; background: #F5F5F5;" |
*Fatigue
*Fatigue
*Cytopenia
*Cytopenia
|-
|-
| Rituximab
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''Rituximab'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Rituximab
*Rituximab
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Infusion related reaction
*Infusion related reaction
*Infections
*Infections
|-
|-
| FR regimen
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''FR regimen'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Fludarabine
*Fludarabine
*Rituximab
*Rituximab
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Neutropenia (63%)
*Neutropenia (63%)
*Thrombocytopenia
*Thrombocytopenia
*Pneumonia
*Pneumonia
|-
|-
| BDR regimen
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''BDR regimen'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Bortezomib
*Bortezomib
*Dexamethasone
*Dexamethasone
*Rituximab
*Rituximab
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Peripheral Neuropathy - reversible in 61% of patients
*Peripheral Neuropathy - reversible in 61% of patients
|-
|-
| DRC regimen
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''DRC regimen'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Dexamethasone
*Dexamethasone
*Rituximab
*Rituximab
*Cyclophosphamide
*Cyclophosphamide
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Neutropenia
*Neutropenia
|-
|-
| CR regimen
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
|  
'''CR regimen'''
| style="padding: 5px 5px; background: #F5F5F5;" |
*Cladribine
*Cladribine
*Rituximab
*Rituximab
|  
| style="padding: 5px 5px; background: #F5F5F5;" |
*Anemia
*Anemia
*Neurological symptoms
*Neurological symptoms

Revision as of 18:27, 17 November 2015

Waldenström's macroglobulinemia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]

Treatment Regimen Drugs Side effects

CHOP-R regimen

  • Cyclophosphamide
  • Doxorubicin
  • Vincristine
  • Prednisone
  • Rituximab
  • Nausea
  • Alopecia
  • Granulocytopenia

Ibrutinib

  • Ibrutinib
  • Fatigue
  • Cytopenia

Rituximab

  • Rituximab
  • Infusion related reaction
  • Infections

FR regimen

  • Fludarabine
  • Rituximab
  • Neutropenia (63%)
  • Thrombocytopenia
  • Pneumonia

BDR regimen

  • Bortezomib
  • Dexamethasone
  • Rituximab
  • Peripheral Neuropathy - reversible in 61% of patients

DRC regimen

  • Dexamethasone
  • Rituximab
  • Cyclophosphamide
  • Neutropenia

CR regimen

  • Cladribine
  • Rituximab
  • Anemia
  • Neurological symptoms
  • Symptomatic cryoglobulinemia
  • Thrombocytopenia


References

Template:WH Template:WS

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