Sandbox: Bone DDx: Difference between revisions

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* Areas of lysis interspersed with areas of sclerosis
* Areas of lysis interspersed with areas of sclerosis
* Lack of periosteal reaction
* Lack of periosteal reaction
* p53 gene mutations

Revision as of 14:10, 23 November 2015

  • 20-30 yo male
  • Gradual dull bone pain at the tibial area
  • Leg swelling
  • Islands of epithelial cells are found in a fibrous stroma
  • Well-demarcated, eccentric/epicenteric, expansile, osteolytic, cortical lesion on X ray
  • Located at the tibial diaphysis
  • Areas of lysis interspersed with areas of sclerosis
  • Lack of periosteal reaction


  • p53 gene mutations