Sandbox: Bone DDx: Difference between revisions

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* 10-20 yo patients
* 40-50 yo women
* Asymptomatic
* History of hyperparathyroidism
* Pathologic fractures


* Often Unremarkable
* Well-defined, purely lytic lesions on X ray
 
* Little reactive bone lesion
* No specific lab finding
* Solid, cystic, or mixed component on MRI
 
*  Cysts contain clear serosanguineous fluid
* Fibrous membranous lining
 
* Well defined geographic lucent lesions on Xray
* Sclerotic margin
* No periosteal reaction
* Thinning of the endosteum and pseudotrabeculation
 
* TP53 mutations

Revision as of 16:17, 23 November 2015

  • 40-50 yo women
  • History of hyperparathyroidism
  • Well-defined, purely lytic lesions on X ray
  • Little reactive bone lesion
  • Solid, cystic, or mixed component on MRI
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