Sandbox: Bone DDx: Difference between revisions

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* Giant cells with round to oval nuclei and nucleoli
* Giant cells with round to oval nuclei and nucleoli
* Elevated number of osteoblast and osteoclast
* Elevated number of osteoblast and osteoclast
* MEN1 gene
* RET oncogene

Revision as of 16:25, 23 November 2015

  • 40-50 yo women
  • History of hyperparathyroidism
  • Well-defined, purely lytic lesions on X ray
  • Little reactive bone lesion
  • Solid, cystic, or mixed component on MRI


  • Fibrosis
  • Giant cells with round to oval nuclei and nucleoli
  • Elevated number of osteoblast and osteoclast
  • MEN1 gene
  • RET oncogene