Sandbox: Bone DDx: Difference between revisions

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* <20 yo males
* Located at the epiphysis
* Joint pain, muscle wasting, tenderness, and swelling/local mass
* Well defined lucent lesions located at the epiphysis
* Lobulated margins with a thin sclerotic rim
* Internal calcifications
* Joint effusion


* Abundant extracellular material
* Abundant extracellular material
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* Calcifications surround cells nests
* Calcifications surround cells nests
* Chickenwire appearance
* Chickenwire appearance


* S100+ve
* S100+ve
* Vimentin +ve
* Vimentin +ve

Revision as of 16:51, 23 November 2015

  • <20 yo males
  • Joint pain, muscle wasting, tenderness, and swelling/local mass
  • Well defined lucent lesions located at the epiphysis
  • Lobulated margins with a thin sclerotic rim
  • Internal calcifications
  • Joint effusion
  • Abundant extracellular material
  • Eosinophilic cytoplasm
  • Calcifications surround cells nests
  • Chickenwire appearance
  • S100+ve
  • Vimentin +ve