Sandbox: Bone DDx: Difference between revisions
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* 30-60 yo males | * 30-60 yo males | ||
* Bone pain | * Bone pain, progressive swelling, decreased range of motion | ||
* | * Pathologic fracture | ||
* | * Positive history of radiation exposure or bone infarct | ||
* Fixed, firm mass to a localized area of tenderness | |||
* Neurologic or vascular defect | |||
* Highly destructive with a wide zone of transition | * Highly destructive with a wide zone of transition |
Revision as of 14:20, 24 November 2015
- 30-60 yo males
- Bone pain, progressive swelling, decreased range of motion
- Pathologic fracture
- Positive history of radiation exposure or bone infarct
- Fixed, firm mass to a localized area of tenderness
- Neurologic or vascular defect
- Highly destructive with a wide zone of transition
- Expansile large soft tissue mass extending from the bone
- Periosteal reaction is uncommon
- Elevated mitotic activity
- Highly cellular fibroblastic proliferation
- Herring bone pattern and spindle cell lesions
- Long dark nuclei with increased granular chromatin
- Scant cytoplasm
- Vimentin +ve